■ 氏名
武内 世生 (タケウチ セイショウ)
TAKEUCHI Seisho

■ 所属部局/職名
Research and Education Faculty, Medical Sciences Cluster, Medical Education Unit/Associate Professor
教育研究部 医療学系 医学教育部門/准教授

■ 学部・学科・コース等
Medical School, School Hospital, Central Clinical Facilities, General Clinical Center
医学部附属病院 中央診療施設 総合診療部

■ 連絡先
住 所
電 話088−880−2515
F A X088-880-2518
E-Mailtakeuti●kochi-u.ac.jp    (送信の際は“●”を半角の“@”に変更して送信してください。)
U R L

■ 出身大学院・研究科等
高知医科大学 博士(医学研究科 発生・形態系) 1993 (修了)

■ 出身学校・専攻等
高知医科大学 (医学部 医学科) 1989 (卒業)

■ 取得学位
博士(医学) (課程) 高知医科大学 血液内科学

■ 研究職歴
1993-2003 高知医科大学 助手
2003-2004 高知大学医学部附属病院 講師
2005- 高知大学医学部附属病院 助教授


■ 委員歴・役員歴

■ 受賞学術賞

■ 所属学会
日本癌学会
 ( 国内)
日本血液学会
 ( 国内)
日本内科学会
 ( 国内)
日本呼吸器学会
 ( 国内)
日本医学教育学会
 ( 国内)
American association for Cancer Research
 ( 国外)

■ 専門分野
臨床推論、総合診療、医療コミュニケーション、入学試験、HIV感染症、感染対策、感染症

■ 主な研究テーマ・活動
悪性腫瘍における遺伝子変異の研究、エイズ・HIV感染症の診療、医学教育、感染対策

■ 研究についてのPR
総合診療という新しい分野からの新たな研究に挑戦しています

■ 社会人・生徒を対象として可能な講演・授業(例えば講演題目)
エイズ・HIV感染症の現状および予防、性教育、ストレスと病気、コミュ二ケーション・医療面接、感染対策、感染症診療

■ 研究業績(論文・解説)
Methylenetetrahydrofolate reductase genotype does not play a role in adult T-cell leukemia/lymphoma pathogenesis among human T-lymphotrophic virus type 1 carriers
 Leukemia Research (Takeuchi S, Takeuchi N, Tsukasaki K, Yang Y, Fermin AC, Tomonaga M, Miller CW, Seo H, Koeffler HP.) 28/, 1039 2004 (学術雑誌)

Allelic loss during progression of follicular lymphoma,
 Leukemia Research (Takeuchi S, de Vos S, Takeuchi N, Fermin AC, Grogan TM, Seo H, Said JW, Koeffler HP) 28/, 567 2004 (学術雑誌)

Allelotype analysis in relapsed childhood acute lymphoblastic leukemia.
 Oncogene (Takeuchi S, Seriu T, van Dongen JJM, Szczepa?ski T, Tsukasaki K, Takeuchi N, Fermin AC, Seo H, Bartram CR, Phillip Koeffler HP) 22/, 6970-6976 2003 (学術雑誌)

Mutations in the Retinoblastoma-related Gene RB2/p130 in Adult T-Cell Leukaemia/Lymphoma.
 Leukemia and Lymphoma (Takeuchi S, Takeuchi N, Tsukasaki K, Fermin AC, de Vos S, Seo H, Koeffler HP) 44/, 699-701 2003 (学術雑誌)

Frameshift mutations in caspase 5 and other target genes in leukemia and lymphoma cell lines having microsatellite instability.
 Leukemia Research (Takeuchi S, Takeuchi N, Fermin AC, Taguchi H, Koeffler HP) 27/, 359-361 2003 (学術雑誌)

Long-Term study of the clinical significance of loss of heterozygosity in childhood acute lymphoblastic leukemia.
 Leukemia (Takeuchi S, Tsukasaki K, Bartram CR, Seriu T, Zimmermann M, Schrappe M, Takeuchi N, Park S, Taguchi H, Koeffler HP) 17/, 149-154 2003 (学術雑誌)

Genetic polymorphisms in the tumor necrosis factor locus in childhood acute lymphoblastic leukaemia.
 British Journal of Haematology (Takeuchi S, Takeuchi N, Tsukasaki K, Bartram CR, Zimmermann M, Schrappe M, Taguchi H, Koeffler HP) 119/, 985-987 2002 (学術雑誌)

Identification of three distinct regions of deletion on the long arm of chromosome 11 in childhood acute lymphoblastic leukemia.
 Oncogene (Takeuchi S, Cho SK, Seriu T, Koike M, Bartram CR, Reiter A, Schrappe M, Takeuchi C, Taguchi H, Koeffler HP) 18/, 7387-7388 1999 (学術雑誌)

The ATM gene and susceptibility to childhood T-cell acute lymphoblastic leukaemia.
 British Journal of Haematology (Takeuchi S, Koike M, Park S, Seriu T, Bartram CR, Taub HE, Williamson IK, Grewal J, Taguchi H, Koeffler HP) 103/, 536-538 1998 (学術雑誌)

Frequent loss of heterozygosity on the long arm of chromosome 6: Identification of two distinct regions of deletion in childhood acute lymphoblastic leukemia.
 Cancer Research (Takeuchi S, Koike M, Seriu T, Bartram CR, Schrappe M, Reiter A, Park S, Taub HE, Kubonishi I, Miyoshi I, Koeffler HP) 58/, 2618-2623 1998 (学術雑誌)

Mutation and expression analysis of the cyclin-dependent kinase inhibitor gene p27/Kipl in pituitary tumors.
 Journal of Endocrinology () 157/, 337-341 1998 ()

Frequent loss of heterozygosity on the long arm of chromosome 6 : Identification of two distinct regions of deletion in childhood acute lymphoblastic Leukemia.
 Cancer Research () 58/, 2618-2623 1998 ()

The ATM gene and susceptibility to childhood T-cell acute lymphoblastic leukaemia
 British Journal of Haematology (Takeuchi S, Koike M, Park S, Seriu T, Bartram CR, Taub HE, Williamson IK, Grewal J, Taguchi H, Koeffler HP) 103/, 536-538 1998 ()

Microsatellite instability and other molecular abnormalities in childhood acute lymphoblastic leukaemia.
 British Journal of Haematology () 98/, 134-139 1997 ()

TEL is one of the targets for deletion on 12p in many cases of childhood B-lineage acute Lymphoblastic Leukemia.
 Leukemia () 11/, 1220-1223 1997 ()

Homozygous deletions at 9p21 in childhood acute lymphoblastic leukemia detected by microsatellite analysis.
 Leukemia () 11/, 1636-1640 1997 ()

Frequent loss of heterozygosity in region of the KIP1 locus in non-small cell lung cancer : Evidence for a new tumor suppressor gene on the short arm of chromosome 12.
 Cancer Research () 56/, 738-740 1996 ()

Acute lymphoblastic leukemia of childhood : Identification of two distinct regions of deletions on the short arm of chromosome 12 in the region of TEL and KIP1.
 Blood () 87/, 3368-3374 1996 ()

Mutations of p53 in wilms' tumors.
 Modern Pathology () 8/, 483-487 1995 ()

Allelotype analysis of childhood acute lymphoblastic leukemia.
 Cancer Research () 55/, 5377-5382 1995 ()

Analysis of a family of cyclin-dependent kinase inhibitors : pl5/MTS2/INK4B, p16/MTS1/INK4A and p18 genes in acute lymphoblastic leukemia of childhood.
 Blood (Takeuchi S, Bartram CR, Seriu T, Miller CW, Tobler A, Janssen JWG, Reiter A, Ludwig W-D, Zimmermann M, Schwaller J, Lee E, Miyoshi I, Koeffler HP) 86/, 755-760 1995 ()

Acute megakaryoblastic leukemia : Establishment of a new cell line (MKPL-1) in vitro and in vivo.
 Leukemia () 6/, 588-594 1992 ()

■ 研究業績(著書)

■ 研究業績(口頭・ポスター)

■ 研究業績(特許)

■ 研究業績(その他の活動)


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