■ 氏名
横山 彰仁 (ヨコヤマ アキヒト)
YOKOYAMA Akihito

■ 所属部局/職名
Research and Education Faculty, Medical Sciences Cluster, Clinical Medicine Unit/Professor
教育研究部 医療学系 臨床医学部門/教授

■ 学部・学科・コース等
Medical School, Medical Course, Department of Respiratory Medicine and Allergology
医学部 医学科 呼吸器・アレルギー内科学

■ 連絡先
住 所
電 話088-880-2345
F A X088-880-2348
E-Mail ayokoyama●kochi-u.ac.jp    (送信の際は“●”を半角の“@”に変更して送信してください。)
U R L

■ 出身大学院・研究科等

■ 出身学校・専攻等

■ 取得学位
医学博士 () 富山大学

■ 研究職歴

■ 委員歴・役員歴

■ 受賞学術賞

■ 所属学会

■ 専門分野
呼吸器病学、アレルギー病学

■ 主な研究テーマ・活動
気管支喘息、COPD、間質性肺炎、肺癌の病態および治療法の研究;気道の免疫機構や呼吸器疾患のバイオマーカーの研究

■ 研究についてのPR
患者さんの真に役立つ新たなバイオマーカーを開発中です

■ 社会人・生徒を対象として可能な講演・授業(例えば講演題目)
呼吸のはなし
アレルギーはなぜ増えた?
間質性肺炎とは?
薬剤によっておこる呼吸器の病気
COPDとは何か
インフルエンザの脅威

■ 研究業績(論文・解説)
Multiple Tracheal Bronchi and a Tracheal Lobe in the Middle Mediastinum.
 American journal of respiratory and critical care medicine (Takaoka M, Ohnishi H, Ujihara A, Yokoyama A) 201/1, e1-e2 202001 () 10.1164/rccm.201905-1054IM

Reconsideration of the cut-off value of angiotensin-converting enzyme for screening of sarcoidosis in Japanese patients.
 Journal of cardiology (Baba Y, Kubo T, Yamanaka S, Ochi Y, Hirota T, Yamasaki N, Ohnishi H, Kubota T, Yokoyama A, Kitaoka H) 74/6, 507-511 201912 () 10.1016/j.jjcc.2019.05.007

Sex-specific differences in the association between birth weight and lung volume in Japanese young adults.
 Respiratory investigation (Anabuki K, Miyamoto S, Akita S, Kubota T, Yokoyama A) 57/6, 598-604 201911 () 10.1016/j.resinv.2019.05.001

Generation and characteristics of a novel "double-hit" high grade B-cell lymphoma cell line DH-My6 with MYC/IGH and BCL6/IGH gene arrangements and potential molecular targeted therapies.
 Oncotarget (Kikuchi H, Higuchi T, Hashida Y, Taniguchi A, Kamioka M, Taguchi T, Yokoyama A, Murakami I, Fujieda M, Daibata M) 9/71, 33482-33499 201809 () 10.18632/oncotarget.26060

Japanese guideline for the treatment of idiopathic pulmonary fibrosis.
 Respiratory investigation (Homma S, Bando M, Azuma A, Sakamoto S, Sugino K, Ishii Y, Izumi S, Inase N, Inoue Y, Ebina M, Ogura T, Kishi K, Kishaba T, Kido T, Gemma A, Goto Y, Sasaki S, Johkoh T, Suda T, Takahashi K, Takahashi H, Taguchi Y, Date H, Taniguchi H, Nakayama T, Nishioka Y, Hasegawa Y, Hattori N, Fukuoka J, Miyamoto A, Mukae H, Yokoyama A, Yoshino I, Watanabe K, Ministry of Health,Labour and Welfare,the Study Group on Diffuse Pulmonary Disorders,Scientific Research/Research on Intractable Diseases,and Japanese Respiratory Society.) 56/4, 268-291 201807 () 10.1016/j.resinv.2018.03.003

TAFRO Syndrome with Disseminated Intravascular Coagulation Successfully Treated with Tocilizumab and Recombinant Thrombomodulin.
 Internal medicine (Tokyo, Japan) (Takayama Y, Kubota T, Ogino Y, Ohnishi H, Togitani K, Yokoyama A) 57/9, 1291-1296 201805 () 10.2169/internalmedicine.9484-17

Hemoptysis from a Ruptured Saphenous Vein Graft Aneurysm.
 Internal medicine (Tokyo, Japan) (Ohnishi H, Arakawa Y, Yokoyama A) 57/1, 143-144 201801 () 10.2169/internalmedicine.9116-17

Clinical utility of fractional exhaled nitric oxide and blood eosinophils counts in the diagnosis of asthma-COPD overlap.
 International journal of chronic obstructive pulmonary disease (Takayama Y, Ohnishi H, Ogasawara F, Oyama K, Kubota T, Yokoyama A) 13/, 2525-2532 2018 () 10.2147/COPD.S167600

In vitro studies on the role of recombinant human soluble thrombomodulin in the context of retinoic acid mediated APL differentiation syndrome.
 Leukemia research (Kojima S, Nishioka C, Chi S, Yokoyama A, Ikezoe T) 63/, 43839 201712 () 10.1016/j.leukres.2017.10.003

Leucine-rich α-2 glycoprotein promotes lung fibrosis by modulating TGF-β signaling in fibroblasts.
 Physiological reports (Honda H, Fujimoto M, Serada S, Urushima H, Mishima T, Lee H, Ohkawara T, Kohno N, Hattori N, Yokoyama A, Naka T) 5/24, 201712 () 10.14814/phy2.13556

Re-certification of respiratory professionals: current practice and the future - educational forum report.
 Breathe (Sheffield, England) (Sehlbach C, Thomson C, Bennett J, Perez de Llano L, Smeenk F, Yokoyama A, Horv?th I, Driessen E, Rohde G) 13/2, 77-80 201706 () 10.1183/20734735.001817

The Fifth Epidermal Growth Factor-like Region of Thrombomodulin Alleviates Murine Graft-versus-Host Disease in a G-Protein Coupled Receptor 15 Dependent Manner.
 Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation (Pan B, Wang X, Kojima S, Nishioka C, Yokoyama A, Honda G, Xu K, Ikezoe T) 23/5, 746-756 201705 () 10.1016/j.bbmt.2017.02.001

MicroRNA-9 plays a role in interleukin-10-mediated expression of E-cadherin in acute myelogenous leukemia cells.
 Cancer science (Nishioka C, Ikezoe T, Pan B, Xu K, Yokoyama A) 108/4, 685-695 201704 () 10.1111/cas.13170

G-protein coupled receptor 15 mediates angiogenesis and cytoprotective function of thrombomodulin.
 Scientific reports (Pan B, Wang X, Nishioka C, Honda G, Yokoyama A, Zeng L, Xu K, Ikezoe T) 7/1, 692 201704 () 10.1038/s41598-017-00781-w

Staphylococcus aureus enterotoxin sensitization involvement and its association with the CysLTR1 variant in different asthma phenotypes.
 Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology (Matsumoto H, Kanemitsu Y, Nagasaki T, Tohda Y, Horiguchi T, Kita H, Kuwabara K, Tomii K, Otsuka K, Fujimura M, Ohkura N, Tomita K, Yokoyama A, Ohnishi H, Nakano Y, Oguma T, Hozawa S, Izuhara Y, Ito I, Oguma T, Inoue H, Tajiri T, Iwata T, Ono J, Ohta S, Hirota T, Kawaguchi T, Tamari M, Yokoyama T, Tabara Y, Matsuda F, Izuhara K, Niimi A, Mishima M) 118/2, 197-203 201702 () 10.1016/j.anai.2016.11.013

The fifth epidermal growth factor like region of thrombomodulin alleviates LPS-induced sepsis through interacting with GPR15.
 Thrombosis and haemostasis (Pan B, Wang X, Kojima S, Nishioka C, Yokoyama A, Honda G, Xu K, Ikezoe T) 117/3, 570-579 201702 () 10.1160/TH16-10-0762

Clinically remitted childhood asthma is associated with airflow obstruction in middle-aged adults.
 Respirology (Carlton, Vic.) (Omori K, Iwamoto H, Yamane T, Nakashima T, Haruta Y, Hattori N, Yokoyama A, Kohno N) 22/1, 86-92 201701 () 10.1111/resp.12860

Association between aerobic capacity and the improvement in glycemic control after the exercise training in type 2 diabetes.
 Diabetology & metabolic syndrome (Nojima H, Yoneda M, Watanabe H, Yamane K, Kitahara Y, Sekikawa K, Yamamoto H, Yokoyama A, Hattori N, Kohno N, Hiroshima University Health Promotion Study group.) 9/, 63 2017 () 10.1186/s13098-017-0262-9

Efficacy and safety of lebrikizumab in patients with uncontrolled asthma (LAVOLTA I and LAVOLTA II): replicate, phase 3, randomised, double-blind, placebo-controlled trials.
 The Lancet. Respiratory medicine (Hanania NA, Korenblat P, Chapman KR, Bateman ED, Kopecky P, Paggiaro P, Yokoyama A, Olsson J, Gray S, Holweg CT, Eisner M, Asare C, Fischer SK, Peng K, Putnam WS, Matthews JG) 4/10, 781-796 201610 () 10.1016/S2213-2600(16)30265-X

Digital necrosis associated with chronic cold haemagglutinin disease.
 British journal of haematology (Mori M, Ikezoe T, Arakawa Y, Yokoyama A) 174/3, 343 201608 () 10.1111/bjh.14169

Identification of electrocardiographic values that indicate chronic obstructive pulmonary disease.
 Heart & lung : the journal of critical care (Ichikawa A, Matsumura Y, Ohnishi H, Kataoka H, Ogura K, Yokoyama A, Sugiura T) 45/4, 359-362 201607 () 10.1016/j.hrtlng.2016.04.004

BCR/ABL increases EZH2 levels which regulates XIAP expression via miRNA-219 in chronic myeloid leukemia cells.
 Leukemia research (Nishioka C, Ikezoe T, Yang J, Yokoyama A) 45/, 24-32 201606 () 10.1016/j.leukres.2016.03.012

[Etiological and exacerbation factors for COPD. Body weight loss].
 Nihon rinsho. Japanese journal of clinical medicine (Yokoyama A) 74/5, 752-756 201605 ()

Carboplatin plus Weekly Paclitaxel with Bevacizumab for First-line Treatment of Non-small Cell Lung Cancer.
 Anticancer research (Kubota T, Okano Y, Sakai M, Takaoka M, Tsukuda T, Anabuki K, Kawase S, Miyamoto S, Ohnishi H, Hatakeyama N, Machida H, Urata T, Yamamoto A, Ogushi F, Yokoyama A) 36/1, 307-312 201601 ()

Sputum Leucine-Rich Alpha-2 Glycoprotein as a Marker of Airway Inflammation in Asthma.
 PloS one (Honda H, Fujimoto M, Miyamoto S, Ishikawa N, Serada S, Hattori N, Nomura S, Kohno N, Yokoyama A, Naka T) 11/9, e0162672 2016 () 10.1371/journal.pone.0162672

The new certification system for internists.
 Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine (Yokoyama A) 104/12, 2539-2546 201512 () 10.2169/naika.104.2539

Blockade of CD82 by a monoclonal antibody potentiates anti-leukemia effects of AraC in vivo.
 Cancer medicine (Nishioka C, Ikezoe T, Yokoyama A) 4/9, 1426-1431 201509 () 10.1002/cam4.482

STAT5A regulates DNMT3A in CD34(+)/CD38(-) AML cells.
 Leukemia research (Takeuchi A, Nishioka C, Ikezoe T, Yang J, Yokoyama A) 39/8, 897-905 201508 () 10.1016/j.leukres.2015.05.006

Successful re-administration of lenalidomide after lenalidomide-induced pulmonary alveolar hemorrhage in a patient with refractory myeloma.
 Annals of hematology (Sakai M, Kubota T, Takaoka M, Tsukuda T, Arakawa Y, Anabuki K, Ikezoe T, Togitani K, Yokoyama A) 94/5, 891-892 201505 () 10.1007/s00277-014-2260-4

Young adult onset systemic Epstein-Barr virus-positive T-cell lymphoproliferative disorders of childhood.
 [Rinsho ketsueki] The Japanese journal of clinical hematology (Sakai M, Togitani K, Tsukuda T, Arakawa Y, Ikezoe T, Hiroi M, Yokoyama A) 56/5, 501-505 201505 () 10.11406/rinketsu.56.501

Co-localization of iron binding on silica with p62/sequestosome1 (SQSTM1) in lung granulomas of mice with acute silicosis.
 Journal of clinical biochemistry and nutrition (Shimizu Y, Dobashi K, Nagase H, Ohta K, Sano T, Matsuzaki S, Ishii Y, Satoh T, Koka M, Yokoyama A, Ohkubo T, Ishii Y, Kamiya T) 56/1, 74-83 201501 () 10.3164/jcbn.14-44

Tetraspanin Family Member, CD82, Regulates Expression of EZH2 via Inactivation of p38 MAPK Signaling in Leukemia Cells.
 PloS one (Nishioka C, Ikezoe T, Yang J, Yokoyama A) 10/5, e0125017 2015 () 10.1371/journal.pone.0125017

Epstein-Barr Virus-Positive Pyothorax-Associated Lymphoma Arising from a Posttraumatic Empyema.
 Acta haematologica (Taniguchi A, Hashida Y, Nemoto Y, Machida H, Chi S, Ikezoe T, Yokoyama A, Daibata M) 134/3, 155-160 2015 () 10.1159/000380809

Using exhaled nitric oxide and serum periostin as a composite marker to identify severe/steroid-insensitive asthma.
 American journal of respiratory and critical care medicine (Nagasaki T, Matsumoto H, Kanemitsu Y, Izuhara K, Tohda Y, Horiguchi T, Kita H, Tomii K, Fujimura M, Yokoyama A, Nakano Y, Hozawa S, Ito I, Oguma T, Izuhara Y, Tajiri T, Iwata T, Ono J, Ohta S, Yokoyama T, Niimi A, Mishima M) 190/12, 1449-1452 201412 () 10.1164/rccm.201407-1290LE

Clinicopathological characteristics and therapeutic outcomes of synchronous gastric adenocarcinoma and gastric lymphoma.
 Anticancer research (Namikawa T, Munekage E, Fukudome I, Maeda H, Kitagawa H, Togitani K, Takasaki M, Yokoyama A, Kobayashi M, Hanazaki K) 34/9, 5067-5074 201409 ()

Seasonal variation of serum KL-6 concentrations is greater in patients with hypersensitivity pneumonitis.
 BMC pulmonary medicine (Ohnishi H, Miyamoto S, Kawase S, Kubota T, Yokoyama A) 14/, 129 201408 () 10.1186/1471-2466-14-129

[Successful eculizumab treatment for multiple coronary thrombosis complicated in paroxysmal nocturnal hemoglobinuria].
 [Rinsho ketsueki] The Japanese journal of clinical hematology (Taniguchi A, Ikezoe T, Takeuchi A, Togitani K, Yoshimoto M, Tanioka K, Kitaoka H, Yokoyama A) 55/8, 965-969 201408 ()

[Series: Emmergency medical care Physicians are needed; MECC (Japanese Medical Emergency Care Course): Current status and future perspective].
 Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine (Suzuki M, Yokoyama A, Suzuki N, Miyazaki S, Saku K, Yamada A, Ohta S, Daida H) 103/8, 1962-1971 201408 () 10.2169/naika.103.1962

Integrating longitudinal information on pulmonary function and inflammation using asthma phenotypes.
 The Journal of allergy and clinical immunology (Nagasaki T, Matsumoto H, Kanemitsu Y, Izuhara K, Tohda Y, Kita H, Horiguchi T, Kuwabara K, Tomii K, Otsuka K, Fujimura M, Ohkura N, Tomita K, Yokoyama A, Ohnishi H, Nakano Y, Oguma T, Hozawa S, Ito I, Oguma T, Inoue H, Tajiri T, Iwata T, Izuhara Y, Ono J, Ohta S, Yokoyama T, Niimi A, Mishima M) 133/5, 1474-7, 1477.e1 201405 () 10.1016/j.jaci.2013.12.1084

Bcr-Abl activates AURKA and AURKB in chronic myeloid leukemia cells via AKT signaling.
 International journal of cancer (Yang J, Ikezoe T, Nishioka C, Udaka K, Yokoyama A) 134/5, 1183-1194 201403 () 10.1002/ijc.28434

Downregulation of miR-217 correlates with resistance of Ph(+) leukemia cells to ABL tyrosine kinase inhibitors.
 Cancer science (Nishioka C, Ikezoe T, Yang J, Nobumoto A, Tsuda M, Yokoyama A) 105/3, 297-307 201403 () 10.1111/cas.12339

[Programs for continuing medical education: B session; 3. Management of COPD and bronchial asthma].
 Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine (Yokoyama A) 103/3, 693-698 201403 () 10.2169/naika.103.693

CD82 regulates STAT5/IL-10 and supports survival of acute myelogenous leukemia cells.
 International journal of cancer (Nishioka C, Ikezoe T, Yang J, Nobumoto A, Kataoka S, Tsuda M, Udaka K, Yokoyama A) 134/1, 55-64 201401 () 10.1002/ijc.28348

Life-threatening pulmonary lymphedema secondary to thoracic duct ligation.
 Internal medicine (Tokyo, Japan) (Ohnishi H, Yamane T, Shiota N, Yokoyama A) 53/20, 2341-2345 2014 () 10.2169/internalmedicine.53.2822

CD34?/CD38? acute myelogenous leukemia cells aberrantly express Aurora kinase A.
 International journal of cancer (Yang J, Ikezoe T, Nishioka C, Nobumoto A, Udaka K, Yokoyama A) 133/11, 2706-2719 201312 () 10.1002/ijc.28277

New findings of kinase switching in gastrointestinal stromal tumor under imatinib using phosphoproteomic analysis.
 International journal of cancer (Takahashi T, Serada S, Ako M, Fujimoto M, Miyazaki Y, Nakatsuka R, Ikezoe T, Yokoyama A, Taguchi T, Shimada K, Kurokawa Y, Yamasaki M, Miyata H, Nakajima K, Takiguchi S, Mori M, Doki Y, Naka T, Nishida T) 133/11, 2737-2743 201312 () 10.1002/ijc.28282

Over-expression of Mcl-1 impairs the ability of ATRA to induce growth arrest and differentiation in acute promyelocytic leukemia cells.
 Apoptosis : an international journal on programmed cell death (Yang J, Ikezoe T, Nishioka C, Yokoyama A) 18/11, 1403-1415 201311 () 10.1007/s10495-013-0872-0

Effect of recombinant human soluble thrombomodulin on clinical outcomes of patients with coagulopathy after hematopoietic stem cell transplantation.
 European journal of haematology (Ikezoe T, Takeuchi A, Chi S, Takaoka M, Anabuki K, Kim T, Sakai M, Taniguchi A, Togitani K, Yokoyama A) 91/5, 442-447 201311 () 10.1111/ejh.12188

Recombinant human soluble thrombomodulin is active against hemophagocytic lymphohistiocytosis associated with acquired immunodeficiency syndrome.
 International journal of hematology (Chi S, Ikezoe T, Takeuchi A, Takaoka M, Yokoyama A) 98/5, 615-619 201311 () 10.1007/s12185-013-1450-5

IL-1β inhibits self-renewal capacity of dormant CD34?/CD38? acute myelogenous leukemia cells in vitro and in vivo.
 International journal of cancer (Yang J, Ikezoe T, Nishioka C, Nobumoto A, Yokoyama A) 133/8, 1967-1981 201310 () 10.1002/ijc.28198

Increased periostin associates with greater airflow limitation in patients receiving inhaled corticosteroids.
 The Journal of allergy and clinical immunology (Kanemitsu Y, Matsumoto H, Izuhara K, Tohda Y, Kita H, Horiguchi T, Kuwabara K, Tomii K, Otsuka K, Fujimura M, Ohkura N, Tomita K, Yokoyama A, Ohnishi H, Nakano Y, Oguma T, Hozawa S, Nagasaki T, Ito I, Oguma T, Inoue H, Tajiri T, Iwata T, Izuhara Y, Ono J, Ohta S, Tamari M, Hirota T, Yokoyama T, Niimi A, Mishima M) 132/2, 305-12.e3 201308 () 10.1016/j.jaci.2013.04.050

[Bronchial asthma: progress in diagnosis and treatments. Topics: II. Pathogenesis and pathophysiology; 4. Severe refractory asthma].
 Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine (Yokoyama A) 102/6, 1378-1383 201306 () 10.2169/naika.102.1378

CD34?/CD38? acute myelogenous leukemia cells aberrantly express CD82 which regulates adhesion and survival of leukemia stem cells.
 International journal of cancer (Nishioka C, Ikezoe T, Furihata M, Yang J, Serada S, Naka T, Nobumoto A, Kataoka S, Tsuda M, Udaka K, Yokoyama A) 132/9, 2006-2019 201305 () 10.1002/ijc.27904

The combination of IκB kinase β inhibitor and everolimus modulates expression of interleukin-10 in human T-cell lymphotropic virus type-1-infected T cells.
 Immunology (Nishioka C, Ikezoe T, Yang J, Udaka K, Yokoyama A) 138/3, 216-227 201303 () 10.1111/imm.12035

A novel lung injury animal model using KL-6-measurable human MUC1-expressing mice.
 Biochemical and biophysical research communications (Sakai M, Kubota T, Ohnishi H, Yokoyama A) 432/3, 460-465 201303 () 10.1016/j.bbrc.2013.01.123

A novel treatment strategy targeting shugoshin 1 in hematological malignancies.
 Leukemia research (Yang J, Ikezoe T, Nishioka C, Yokoyama A) 37/1, 76-82 201301 () 10.1016/j.leukres.2012.10.002

Cross-sectional and prospective study of the association between lung function and prediabetes.
 BMJ open (Yamane T, Yokoyama A, Kitahara Y, Miyamoto S, Haruta Y, Hattori N, Yamane K, Hara H, Kohno N) 3/2, 2013 () 10.1136/bmjopen-2012-002179

Different MUC1 gene polymorphisms in German and Japanese ethnicities affect serum KL-6 levels.
 Respiratory medicine (Horimasu Y, Hattori N, Ishikawa N, Kawase S, Tanaka S, Yoshioka K, Yokoyama A, Kohno N, Bonella F, Guzman J, Ohshimo S, Costabel U) 106/12, 1756-1764 201212 () 10.1016/j.rmed.2012.09.001

Recombinant human soluble thrombomodulin safely and effectively rescues acute promyelocytic leukemia patients from disseminated intravascular coagulation.
 Leukemia research (Ikezoe T, Takeuchi A, Isaka M, Arakawa Y, Iwabu N, Kin T, Anabuki K, Sakai M, Taniguchi A, Togitani K, Yokoyama A) 36/11, 1398-1402 201211 () 10.1016/j.leukres.2012.08.012

Thrombomodulin protects endothelial cells from a calcineurin inhibitor-induced cytotoxicity by upregulation of extracellular signal-regulated kinase/myeloid leukemia cell-1 signaling.
 Arteriosclerosis, thrombosis, and vascular biology (Ikezoe T, Yang J, Nishioka C, Honda G, Furihata M, Yokoyama A) 32/9, 2259-2270 201209 () 10.1161/ATVBAHA.112.251157

Thrombomodulin enhances the antifibrinolytic and antileukemic effects of all-trans retinoic acid in acute promyelocytic leukemia cells.
 Experimental hematology (Ikezoe T, Yang J, Nishioka C, Isaka M, Iwabu N, Sakai M, Taniguchi A, Honda G, Yokoyama A) 40/6, 457-465 201206 () 10.1016/j.exphem.2012.01.016

Cigarette smoking decreases dynamic inspiratory capacity during maximal exercise in patients with type 2 diabetes.
 Hiroshima journal of medical sciences (Kitahara Y, Hattori N, Yokoyama A, Yamane K, Sekikawa K, Inamizu T, Kohno N) 61/2, 29-36 201206 ()

Thrombomodulin-induced differentiation of acute myelomonocytic leukemia cells via JNK signaling.
 Leukemia research (Yang J, Ikezoe T, Nishioka C, Honda G, Yokoyama A) 36/5, 625-633 201205 () 10.1016/j.leukres.2012.01.019

Promoter methylation of the bone morphogenetic protein 6 gene in multiple myeloma.
 Oncology reports (Hashida Y, Nemoto Y, Imajoh M, Murakami M, Taniguchi A, Komatsu N, Yokoyama A, Daibata M) 27/3, 825-830 201203 () 10.3892/or.2011.1548

Utility of KL-6/MUC1 in the clinical management of interstitial lung diseases.
 Respiratory investigation (Ishikawa N, Hattori N, Yokoyama A, Kohno N) 50/1, 43903 201203 () 10.1016/j.resinv.2012.02.001

Long-term exposure of gastrointestinal stromal tumor cells to sunitinib induces epigenetic silencing of the PTEN gene.
 International journal of cancer (Yang J, Ikezoe T, Nishioka C, Takezaki Y, Hanazaki K, Taguchi T, Yokoyama A) 130/4, 959-966 201202 () 10.1002/ijc.26095

Krebs von den Lungen-6 (KL-6) is a prognostic biomarker in patients with surgically resected nonsmall cell lung cancer.
 International journal of cancer (Tanaka S, Hattori N, Ishikawa N, Shoda H, Takano A, Nishino R, Okada M, Arihiro K, Inai K, Hamada H, Yokoyama A, Kohno N) 130/2, 377-387 201201 () 10.1002/ijc.26007

Interferon (alpha, beta and omega) receptor 2 is a prognostic biomarker for lung cancer.
 Pathobiology : journal of immunopathology, molecular and cellular biology (Tanaka S, Hattori N, Ishikawa N, Horimasu Y, Deguchi N, Takano A, Tomoda Y, Yoshioka K, Fujitaka K, Arihiro K, Okada M, Yokoyama A, Kohno N) 79/1, 24-33 2012 () 10.1159/000331230

Intra-airway administration of small interfering RNA targeting plasminogen activator inhibitor-1 attenuates allergic asthma in mice.
 American journal of physiology. Lung cellular and molecular physiology (Miyamoto S, Hattori N, Senoo T, Onari Y, Iwamoto H, Kanehara M, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Yokoyama A, Kohno N) 301/6, L908-16 201112 () 10.1152/ajplung.00115.2011

[The relationships between the peak inspiratory flow and the characteristics factors in the asthmatics with inhaled corticosteroid -a multicenter study in Chugoku Shikoku area].
 Arerugi = [Allergy] (Obase Y, Kanehiro A, Tanimoto Y, Miyahara N, Oka M, Eda R, Kubota T, Yokoyama A, Wakabayashi K, Takeyama H, Okada C, Kimura G, Soda R, Takahashi K, Tanimoto M) 60/12, 1621-1629 201112 ()

Expression of p-JAK2 predicts clinical outcome and is a potential molecular target of acute myelogenous leukemia.
 International journal of cancer (Ikezoe T, Kojima S, Furihata M, Yang J, Nishioka C, Takeuchi A, Isaka M, Koeffler HP, Yokoyama A) 129/10, 2512-2521 201111 () 10.1002/ijc.25910

Association of airway inflammation with asthma control level evaluated by the asthma control test.
 The Journal of asthma : official journal of the Association for the Care of Asthma (Shiota N, Yokoyama A, Haruta Y, Hattori N, Kohno N) 48/9, 907-913 201111 () 10.3109/02770903.2011.615430

Chronic hepatitis C virus infection is associated with more severe asthma.
 Allergology international : official journal of the Japanese Society of Allergology (Nakashima T, Yokoyama A, Ohnishi H, Yamasaki M, Shiode M, Haruta Y, Hattori N, Hozawa S, Yamakido H, Kohno N) 60/3, 299-304 201109 () 10.2332/allergolint.10-OA-0240

In-air microparticle induced X-ray emission analysis of particles in interstitial pneumonia lung tissue obtained by transbronchial biopsy.
 Journal of clinical biochemistry and nutrition (Shimizu Y, Matsuzaki S, Satoh T, Koka M, Yokoyama A, Ohkubo T, Ishii Y, Kamiya T, Fueki M, Mori M, Dobashi K) 49/2, 125-130 201109 () 10.3164/jcbn.10-127

Simultaneous inhibition of DNA methyltransferase and histone deacetylase induces p53-independent apoptosis via down-regulation of Mcl-1 in acute myelogenous leukemia cells.
 Leukemia research (Nishioka C, Ikezoe T, Yang J, Udaka K, Yokoyama A) 35/7, 932-939 201107 () 10.1016/j.leukres.2011.04.004

Change in serum KL-6 level from baseline is useful for predicting life-threatening EGFR-TKIs induced interstitial lung disease.
 Respiratory research (Kawase S, Hattori N, Ishikawa N, Horimasu Y, Fujitaka K, Furonaka O, Isobe T, Miyoshi S, Hamada H, Yamane T, Yokoyama A, Kohno N) 12/, 97 201107 () 10.1186/1465-9921-12-97

A pilot study of the multiherb Kampo medicine bakumondoto for cough in patients with chronic obstructive pulmonary disease.
 Phytomedicine : international journal of phytotherapy and phytopharmacology (Mukaida K, Hattori N, Kondo K, Morita N, Murakami I, Haruta Y, Yokoyama A, Kohno N) 18/44052, 625-629 201106 () 10.1016/j.phymed.2010.11.006

Diffuse alveolar hemorrhage associated with lenalidomide.
 International journal of hematology (Sakai M, Kubota T, Kuwayama Y, Ikezoe T, Yokoyama A) 93/6, 830-831 201106 () 10.1007/s12185-011-0871-2

Elemental analysis of lung tissue particles and intracellular iron content of alveolar macrophages in pulmonary alveolar proteinosis.
 Respiratory research (Shimizu Y, Matsuzaki S, Dobashi K, Yanagitani N, Satoh T, Koka M, Yokoyama A, Ohkubo T, Ishii Y, Kamiya T, Mori M) 12/, 88 201106 () 10.1186/1465-9921-12-88

Inhibition of signal transducer and activator of transcription 5 by the inhibitor of janus kinases stimulates dormant human leukemia CD34+ /CD38- cells and sensitizes them to antileukemia agents.
 International journal of cancer (Ikezoe T, Yang J, Nishioka C, Kojima S, Takeuchi A, Phillip Koeffler H, Yokoyama A) 128/10, 2317-2325 201105 () 10.1002/ijc.25806

Effect of mustard gas exposure on incidence of lung cancer: a longitudinal study.
 American journal of epidemiology (Doi M, Hattori N, Yokoyama A, Onari Y, Kanehara M, Masuda K, Tonda T, Ohtaki M, Kohno N) 173/6, 659-666 201103 () 10.1093/aje/kwq426

Mucins carrying selectin ligands as predictive biomarkers of disseminated intravascular coagulation complication in ARDS.
 Chest (Nakashima T, Yokoyama A, Inata J, Ishikawa N, Haruta Y, Hattori N, Kohno N) 139/2, 296-304 201102 () 10.1378/chest.09-3082

Levels of surfactant proteins A and D and KL-6 are elevated in the induced sputum of chronic obstructive pulmonary disease patients: a sequential sputum analysis.
 Respiration; international review of thoracic diseases (Ishikawa N, Hattori N, Tanaka S, Horimasu Y, Haruta Y, Yokoyama A, Kohno N, Kinnula VL) 82/1, 44122 2011 () 10.1159/000324539

AZ960, a novel Jak2 inhibitor, induces growth arrest and apoptosis in adult T-cell leukemia cells.
 Molecular cancer therapeutics (Yang J, Ikezoe T, Nishioka C, Furihata M, Yokoyama A) 9/12, 3386-3395 201012 () 10.1158/1535-7163.MCT-10-0416

Successful treatment of thrombotic thrombocytopenic purpura associated with systemic lupus erythematosus with recombinant human soluble thrombomodulin.
 Thrombosis research (Sakai M, Ikezoe T, Bandobashi K, Yokoyama A) 126/5, e392-3 201011 () 10.1016/j.thromres.2010.06.024

[A case of sarcoidosis following chemotherapy for follicular lymphoma].
 Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society (Sakai M, Bandobashi K, Ikezoe T, Kubota T, Yokoyama A) 48/10, 774-778 201010 ()

Epstein-Barr virus-infected subcutaneous panniculitis-like T-cell lymphoma associated with methotrexate treatment.
 International journal of hematology (Nemoto Y, Taniguchi A, Kamioka M, Nakaoka Y, Hiroi M, Yokoyama A, Enzan H, Daibata M) 92/2, 364-368 201009 () 10.1007/s12185-010-0642-5

Successful treatment of imatinib-resistant hypereosinophilic syndrome with nilotinib.
 Leukemia research (Ikezoe T, Togitani K, Tasaka T, Nishioka C, Yokoyama A) 34/8, e200-1 201008 () 10.1016/j.leukres.2010.02.024

Inhibition of mTORC1 by RAD001 (everolimus) potentiates the effects of 1,25-dihydroxyvitamin D(3) to induce growth arrest and differentiation of AML cells in vitro and in vivo.
 Experimental hematology (Yang J, Ikezoe T, Nishioka C, Ni L, Koeffler HP, Yokoyama A) 38/8, 666-676 201008 () 10.1016/j.exphem.2010.03.020

Inhibition of MEK/ERK signaling induces apoptosis of acute myelogenous leukemia cells via inhibition of eukaryotic initiation factor 4E-binding protein 1 and down-regulation of Mcl-1.
 Apoptosis : an international journal on programmed cell death (Nishioka C, Ikezoe T, Yang J, Yokoyama A) 15/7, 795-804 201007 () 10.1007/s10495-010-0483-y

[Interleukin-6 (IL-6)/soluble IL-6 receptor(sIL-6R)].
 Nihon rinsho. Japanese journal of clinical medicine (Kubota T, Yokoyama A) 68 Suppl 7/, 75-77 201007 ()

Suppression of plasminogen activator inhibitor-1 by RNA interference attenuates pulmonary fibrosis.
 Thorax (Senoo T, Hattori N, Tanimoto T, Furonaka M, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Yokoyama A, Kohno N) 65/4, 334-340 201004 () 10.1136/thx.2009.119974

The influence of lung function on exercise capacity in patients with type 2 diabetes.
 Hiroshima journal of medical sciences (Kitahara Y, Hattori N, Yokoyama A, Yamane K, Sekikawa K, Inamizu T, Kohno N) 59/1, 44025 201003 ()

Productive cough is an independent risk factor for the development of COPD in former smokers.
 Respirology (Carlton, Vic.) (Yamane T, Hattori N, Kitahara Y, Haruta Y, Sasaki H, Yokoyama A, Kohno N) 15/2, 313-318 201002 () 10.1111/j.1440-1843.2009.01682.x

p53 is critical for the Aurora B kinase inhibitor-mediated apoptosis in acute myelogenous leukemia cells.
 International journal of hematology (Ikezoe T, Yang J, Nishioka C, Yokoyama A) 91/1, 69-77 201001 () 10.1007/s12185-009-0462-7

Analysis of Aurora B kinase in non-Hodgkin lymphoma.
 Laboratory investigation; a journal of technical methods and pathology (Ikezoe T, Takeuchi T, Yang J, Adachi Y, Nishioka C, Furihata M, Koeffler HP, Yokoyama A) 89/12, 1364-1373 200912 () 10.1038/labinvest.2009.106

Inhibition of mammalian target of rapamycin signaling potentiates the effects of all-trans retinoic acid to induce growth arrest and differentiation of human acute myelogenous leukemia cells.
 International journal of cancer (Nishioka C, Ikezoe T, Yang J, Gery S, Koeffler HP, Yokoyama A) 125/7, 1710-1720 200910 () 10.1002/ijc.24472

Blockade of MEK signaling potentiates 5-Aza-2'-deoxycytidine-induced apoptosis and upregulation of p21(waf1) in acute myelogenous leukemia cells.
 International journal of cancer (Nishioka C, Ikezoe T, Yang J, Komatsu N, Koeffler HP, Yokoyama A) 125/5, 1168-1176 200909 () 10.1002/ijc.24377

Inhibition of MEK signaling enhances the ability of cytarabine to induce growth arrest and apoptosis of acute myelogenous leukemia cells.
 Apoptosis : an international journal on programmed cell death (Nishioka C, Ikezoe T, Yang J, Yokoyama A) 14/9, 1108-1120 200909 () 10.1007/s10495-009-0372-4

Lymphocyte transformation test is not helpful for the diagnosis of methotrexate-induced pneumonitis in patients with rheumatoid arthritis.
 Clinica chimica acta; international journal of clinical chemistry (Hirata S, Hattori N, Kumagai K, Haruta Y, Yokoyama A, Kohno N) 407/43832, 25-29 200909 () 10.1016/j.cca.2009.06.024

[A case of tumor microembolism diagnosed by perfusion scan and transbronchial lung biopsy].
 Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society (Iwamoto H, Sakai M, Yamane T, Shiota N, Shoda H, Bandobashi K, Kubota T, Yokoyama A) 47/8, 687-691 200908 ()

Genetic ablation of the Bach1 gene reduces hyperoxic lung injury in mice: role of IL-6.
 Free radical biology & medicine (Tanimoto T, Hattori N, Senoo T, Furonaka M, Ishikawa N, Fujitaka K, Haruta Y, Yokoyama A, Igarashi K, Kohno N) 46/8, 1119-1126 200904 () 10.1016/j.freeradbiomed.2009.01.017

Perceived stress, severity of asthma, and quality of life in young adults with asthma.
 Allergology international : official journal of the Japanese Society of Allergology (Kimura T, Yokoyama A, Kohno N, Nakamura H, Eboshida A) 58/1, 71-79 200903 () 10.2332/allergolint.O-07-531

Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice.
 The Journal of pharmacology and experimental therapeutics (Furonaka M, Hattori N, Tanimoto T, Senoo T, Ishikawa N, Fujitaka K, Haruta Y, Yokoyama A, Kohno N) 328/1, 55-61 200901 () 10.1124/jpet.108.141721

Airflow limitation in smokers is associated with subclinical atherosclerosis.
 American journal of respiratory and critical care medicine (Iwamoto H, Yokoyama A, Kitahara Y, Ishikawa N, Haruta Y, Yamane K, Hattori N, Hara H, Kohno N) 179/1, 35-40 200901 () 10.1164/rccm.200804-560OC

Metastatic breast cancer presenting as air-space consolidation on chest computed tomography.
 Internal medicine (Tokyo, Japan) (Ohnishi H, Haruta Y, Yokoyama A, Nakashima T, Hattori N, Kohno N) 48/9, 727-731 2009 () 10.2169/internalmedicine.48.1849

Anti-inflammatory effects and clinical efficacy of theophylline and tulobuterol in mild-to-moderate chronic obstructive pulmonary disease.
 Pulmonary pharmacology & therapeutics (Kanehara M, Yokoyama A, Tomoda Y, Shiota N, Iwamoto H, Ishikawa N, Taooka Y, Haruta Y, Hattori N, Kohno N) 21/6, 874-878 200812 () 10.1016/j.pupt.2008.09.003

Ultrastructural study of the morphogenesis of human herpesvirus 6 type B in human T-lymphotropic virus type I-producing lymphoid cells.
 Medical molecular morphology (Ohtsuki Y, Daibata M, Bandobashi K, Lee GH, Furihata M, Yokoyama A, Miyoshi I) 41/4, 204-210 200812 () 10.1007/s00795-008-0413-z

Megakaryocyte potentiating factor as a tumor marker of malignant pleural mesothelioma: evaluation in comparison with mesothelin.
 Lung cancer (Amsterdam, Netherlands) (Iwahori K, Osaki T, Serada S, Fujimoto M, Suzuki H, Kishi Y, Yokoyama A, Hamada H, Fujii Y, Yamaguchi K, Hirashima T, Matsui K, Tachibana I, Nakamura Y, Kawase I, Naka T) 62/1, 45-54 200810 () 10.1016/j.lungcan.2008.02.012

Promoter methylation of the bone morphogenetic protein-6 gene in association with adult T-cell leukemia.
 International journal of cancer (Taniguchi A, Nemoto Y, Yokoyama A, Kotani N, Imai S, Shuin T, Daibata M) 123/8, 1824-1831 200810 () 10.1002/ijc.23749

MS-275, a novel histone deacetylase inhibitor with selectivity against HDAC1, induces degradation of FLT3 via inhibition of chaperone function of heat shock protein 90 in AML cells.
 Leukemia research (Nishioka C, Ikezoe T, Yang J, Takeuchi S, Koeffler HP, Yokoyama A) 32/9, 1382-1392 200809 () 10.1016/j.leukres.2008.02.018

Immunohistochemical localisation of surfactant proteins A and D, and KL-6 in pulmonary alveolar proteinosis.
 Pathology (Ohtsuki Y, Kobayashi M, Yoshida S, Kishimoto N, Kubo K, Yokoyama A, Lee GH, Furihata M) 40/5, 536-539 200808 () 10.1080/00313020802198077

Blockade of MEK/ERK signaling enhances sunitinib-induced growth inhibition and apoptosis of leukemia cells possessing activating mutations of the FLT3 gene.
 Leukemia research (Nishioka C, Ikezoe T, Yang J, Takeshita A, Taniguchi A, Komatsu N, Togitani K, Koeffler HP, Yokoyama A) 32/6, 865-872 200806 () 10.1016/j.leukres.2007.09.017

DHMEQ, a novel nuclear factor-kappaB inhibitor, induces selective depletion of alloreactive or phytohaemagglutinin-stimulated peripheral blood mononuclear cells, decreases production of T helper type 1 cytokines, and blocks maturation of dendritic cells.
 Immunology (Nishioka C, Ikezoe T, Jing Y, Umezawa K, Yokoyama A) 124/2, 198-205 200806 () 10.1111/j.1365-2567.2007.02755.x

Ki11502, a novel multitargeted receptor tyrosine kinase inhibitor, induces growth arrest and apoptosis of human leukemia cells in vitro and in vivo.
 Blood (Nishioka C, Ikezoe T, Yang J, Miwa A, Tasaka T, Kuwayama Y, Togitani K, Koeffler HP, Yokoyama A) 111/10, 5086-5092 200805 () 10.1182/blood-2007-06-098079

Suppressor of cytokine signaling 1 inhibits pulmonary inflammation and fibrosis.
 The Journal of allergy and clinical immunology (Nakashima T, Yokoyama A, Onari Y, Shoda H, Haruta Y, Hattori N, Naka T, Kohno N) 121/5, 1269-1276 200805 () 10.1016/j.jaci.2008.02.003

Effect of aerobic exercise training on oxidative stress in patients with type 2 diabetes mellitus.
 Metabolism: clinical and experimental (Nojima H, Watanabe H, Yamane K, Kitahara Y, Sekikawa K, Yamamoto H, Yokoyama A, Inamizu T, Asahara T, Kohno N, Hiroshima University Health Promotion Study Group.) 57/2, 170-176 200802 () 10.1016/j.metabol.2007.08.021

A case of pulmonary asbestosis presenting with temporal arteritis involving multiple medium-sized vessels.
 Modern rheumatology (Hirata S, Hattori N, Ishikawa N, Fujitaka K, Kumagai K, Taooka Y, Haruta Y, Yokoyama A, Kohno N) 18/1, 100-104 2008 () 10.1007/s10165-007-0016-x

[Cytopathological features of multiple myeloma].
 Nihon rinsho. Japanese journal of clinical medicine (Takeuchi T, Adachi Y, Ikezoe T, Yokoyama A, Furihata M, Ohtsuki Y) 65/12, 2250-2255 200712 ()

AZD1152, a novel and selective aurora B kinase inhibitor, induces growth arrest, apoptosis, and sensitization for tubulin depolymerizing agent or topoisomerase II inhibitor in human acute leukemia cells in vitro and in vivo.
 Blood (Yang J, Ikezoe T, Nishioka C, Tasaka T, Taniguchi A, Kuwayama Y, Komatsu N, Bandobashi K, Togitani K, Koeffler HP, Taguchi H, Yokoyama A) 110/6, 2034-2040 200709 () 10.1182/blood-2007-02-073700

Circulating KL-6/MUC1 mucin carrying sialyl Lewisa oligosaccharide is an independent prognostic factor in patients with lung adenocarcinoma.
 International journal of cancer (Inata J, Hattori N, Yokoyama A, Ohshimo S, Doi M, Ishikawa N, Hamada H, Kohno N) 120/12, 2643-2649 200706 () 10.1002/ijc.22613

[Approach to the diagnosis of drug-induced lung diseases].
 Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine (Yokoyama A) 96/6, 1097-1103 200706 () 10.2169/naika.96.1097

Overproduction of collagen and diminished SOCS1 expression are causally linked in fibroblasts from idiopathic pulmonary fibrosis.
 Biochemical and biophysical research communications (Shoda H, Yokoyama A, Nishino R, Nakashima T, Ishikawa N, Haruta Y, Hattori N, Naka T, Kohno N) 353/4, 1004-1010 200702 () 10.1016/j.bbrc.2006.12.128

Significance of serum uric acid in patients with chronic respiratory failure treated with non-invasive positive pressure ventilation.
 Internal medicine (Tokyo, Japan) (Kadowaki T, Hamada H, Yokoyama A, Abe M, Nishimura K, Kohno N, Inata J, Kuraoka T, Moritani C, Higaki J) 46/11, 691-697 2007 () 10.2169/internalmedicine.46.6120

Effect of CPAP on brachial-ankle pulse wave velocity in patients with OSAHS: an open-labelled study.
 Respiratory medicine (Kitahara Y, Hattori N, Yokoyama A, Nakajima M, Kohno N) 100/12, 2160-2169 200612 () 10.1016/j.rmed.2006.03.015

[Update in asthma therapy. Inhalation steroids].
 Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine (Hamada H, Yokoyama A) 95/8, 1458-1463 200608 () 10.2169/naika.95.1458

Anti-tumor effect of the anti-KL-6/MUC1 monoclonal antibody through exposure of surface molecules by MUC1 capping.
 Cancer science (Doi M, Yokoyama A, Kondo K, Ohnishi H, Ishikawa N, Hattori N, Kohno N) 97/5, 420-429 200605 () 10.1111/j.1349-7006.2006.00183.x

Effect of inhaled bronchodilators on air trapping in patients with stable asthma.
 The Journal of asthma : official journal of the Association for the Care of Asthma (Ito R, Yokoyama A, Hamada H, Yasuhara Y, Kohno N, Higaki J) 43/2, 125-129 200603 () 10.1080/02770900500498287

Novel orthotopic implantation model of human malignant pleural mesothelioma (EHMES-10 cells) highly expressing vascular endothelial growth factor and its receptor.
 Cancer science (Nakataki E, Yano S, Matsumori Y, Goto H, Kakiuchi S, Muguruma H, Bando Y, Uehara H, Hamada H, Kito K, Yokoyama A, Sone S) 97/3, 183-191 200603 () 10.1111/j.1349-7006.2006.00163.x

Prognostic value of circulating KL-6 in idiopathic pulmonary fibrosis.
 Respirology (Carlton, Vic.) (Yokoyama A, Kondo K, Nakajima M, Matsushima T, Takahashi T, Nishimura M, Bando M, Sugiyama Y, Totani Y, Ishizaki T, Ichiyasu H, Suga M, Hamada H, Kohno N) 11/2, 164-168 200603 () 10.1111/j.1440-1843.2006.00834.x

KL-6, a human MUC1 mucin, promotes proliferation and survival of lung fibroblasts.
 Biochemical and biophysical research communications (Ohshimo S, Yokoyama A, Hattori N, Ishikawa N, Hirasawa Y, Kohno N) 338/4, 1845-1852 200512 () 10.1016/j.bbrc.2005.10.144

Circulating aminopeptidase N/CD13 is an independent prognostic factor in patients with non-small cell lung cancer.
 Clinical cancer research : an official journal of the American Association for Cancer Research (Murakami H, Yokoyama A, Kondo K, Nakanishi S, Kohno N, Miyake M) 11/24 Pt 1, 8674-8679 200512 () 10.1158/1078-0432.CCR-05-1005

Thymic carcinoma originating from the mid-posterior mediastinum.
 Respirology (Carlton, Vic.) (Kadowaki T, Hamada H, Yokoyama A, Katayama H, Aramoto T, Ueda N, Tomioka H, Higaki J) 10/5, 689-691 200511 () 10.1111/j.1440-1843.2005.00771.x

[Interleukin-6 (IL-6) /soluble IL-6 receptor].
 Nihon rinsho. Japanese journal of clinical medicine (Yokoyama A) 63 Suppl 8/, 72-74 200508 ()

Polymorphism of the MUC1 mucin gene is associated with susceptibility to lung adenocarcinoma and poor prognosis.
 Oncology reports (Mitsuta K, Yokoyama A, Kondo K, Nakajima M, Arita K, Kohno N) 14/1, 185-189 200507 ()

Two cases of primary pulmonary osteosarcoma.
 Internal medicine (Tokyo, Japan) (Kadowaki T, Hamada H, Yokoyama A, Katayama H, Abe M, Nishimura K, Tomiyama N, Kito K, Miyazaki T, Higaki J) 44/6, 632-637 200506 () 10.2169/internalmedicine.44.632

Neutropenic enterocolitis in lung cancer: a report of two cases and a review of the literature.
 Internal medicine (Tokyo, Japan) (Furonaka M, Miyazaki M, Nakajima M, Hirata S, Fujitaka K, Kondo K, Yokoyama A, Maeda H, Kohno N) 44/5, 467-470 200505 () 10.2169/internalmedicine.44.467

Hemoperitoneum secondary to spontaneous rupture of hepatic metastasis from lung cancer.
 Internal medicine (Tokyo, Japan) (Kadowaki T, Hamada H, Yokoyama A, Ito R, Ishimaru S, Ohnishi H, Katayama H, Oshima M, Okura T, Kito K, Higaki J) 44/4, 290-293 200504 () 10.2169/internalmedicine.44.290

Successful treatment of obstructive sleep apnea syndrome improves autonomic nervous system dysfunction.
 Clinical and experimental hypertension (New York, N.Y. : 1993) (Ito R, Hamada H, Yokoyama A, Oshima M, Katayama H, Ohnishi H, Kadowaki T, Ishimaru S, Irifune K, Higaki J) 27/43864, 259-267 200502 ()

Metastatic renal cell carcinoma presenting as multiple pleural tumours.
 Respirology (Carlton, Vic.) (Ohnishi H, Abe M, Hamada H, Yokoyama A, Hirayama T, Ito R, Nishimura K, Higaki J) 10/1, 128-131 200501 () 10.1111/j.1440-1843.2005.00652.x

Pulmonary edema in pheochromocytoma.
 Internal medicine (Tokyo, Japan) (Kondo K, Yokoyama A, Nakajima M, Kohno N) 43/12, 1101-1102 200412 () 10.2169/internalmedicine.43.1101

[Clinical study on bronchial asthma and leukotriene antagonists].
 Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine (Yokoyama A) 93/12, 2656-2661 200412 () 10.2169/naika.93.2656

[A case of primary adenocarcinoma of the trachea].
 Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society (Ishimaru S, Katayama H, Hamada H, Yokoyama A, Kadowaki T, Ito R, Iwamoto Y, Miyazawa T, Higaki J) 42/11, 966-969 200411 ()

[A case of interstitial pneumonia caused by gosha-jinki-gan].
 Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics (Katayama H, Hamada H, Yokoyama A, Kadowaki T, Ito R, Higaki J) 41/6, 675-678 200411 () 10.3143/geriatrics.41.675

Clarithromycin-induced eosinophilic pneumonia.
 Internal medicine (Tokyo, Japan) (Ohnishi H, Abe M, Yokoyama A, Hamada H, Ito R, Hirayama T, Nishimura K, Higaki J) 43/3, 231-235 200403 () 10.2169/internalmedicine.43.231

Circulating natural killer T cells in patients with asthma.
 The Journal of asthma : official journal of the Association for the Care of Asthma (Ikegami Y, Yokoyama A, Haruta Y, Hiyama K, Kohno N) 41/8, 877-882 2004 () 10.1081/jas-200038364

[Successful treatment of bronchiolitis obliterans organizing pneumonia with cyclosporin and steroids].
 Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society (Katayama H, Yokoyama A, Hamada H, Irita J, Kadowaki T, Ito R, Onishi H, Watanabe A, Mutsukado Y, Kukita H, Hiwada K, Higaki J) 41/8, 551-555 200308 ()

[Bronchial asthma].
 Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine (Yokoyama A) 92/7, 1272-1278 200307 ()

Comparative study of KL-6, surfactant protein-A, surfactant protein-D, and monocyte chemoattractant protein-1 as serum markers for interstitial lung diseases.
 American journal of respiratory and critical care medicine (Ohnishi H, Yokoyama A, Kondo K, Hamada H, Abe M, Nishimura K, Hiwada K, Kohno N) 165/3, 378-381 200202 () 10.1164/ajrccm.165.3.2107134

[A case of central diabetes insipidus caused by metastatic small cell lung cancer].
 Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society (Irifune K, Hamada H, Yokoyama A, Kondo K, Kohno N, Hara Y, Hiwada K) 40/2, 154-159 200202 ()

AA-2414の高年齢気管支喘息患者における有効性および安全性の検討 ?Efficacy and safety of AA-2414 on bronchial asthma in the elderly?
 臨床医薬 () 9/, 185-211 1993 ()

タザノラスト(タザノール®)の気管支喘息に対する効果
 Therapeutic Research () 15/, 3763-3772 1994 ()

肺癌化学療法症例に対する rhG-CSF (グラン®) の臨床効果 ー多施設による検討ー
 Therapeutic Research () 15/, 4607-4611 1994 ()

呼吸器感染症に対するセフポドキシム・プロキセチル(バナン®錠)の臨床的検討ー多施設による検討ー
 Progress in Medicine () 15/, 81-85 1995 ()

気管支喘息患者におけるボルマチックを用いたプロピオン酸ベクロメタゾン吸入薬1日800μg, 1日2回分割投与法の有用性の検討
 新薬と臨牀 () 44/, 1989-1998 1995 ()

研究室訪問ー愛媛大学医学部第2内科ー
 分子呼吸器病 () 2/, 140-141 1998 ()

洞機能不全症候群を合併した特発性起立性低血圧症の1症例
 日本老年医学会雑誌 (酒井 希美子, 間口 元文, 小原 克彦, 西田 亙, 若宮 留美, 中村 尚子, 向井 幹夫, 横山 彰仁, 日和田 邦男) 33/2, 105-109 1996 () 10.3143/geriatrics.33.105

気管支肺胞洗浄液中CA19-9の測定が治療方針決定に有用であった肺胞上皮癌の1例
 日本内科学会雑誌 (阿部 聖裕, 山本 浩三, 高田 康徳, 伊東 亮治, 近藤 圭一, 藤野 俊, 藤岡 精二, 平澤 泰, 横山 彰仁, 河野 修興, 日和田 邦男) 85/6, 925-926 1997 () 10.2169/naika.85.925

クッシング症候群を合併したACTH,PTH産生肺小細胞癌の1例
 日本老年医学会雑誌 (佐藤 澄子, 横山 彰仁, 大塚 知明, 野本 高彦, 阿部 聖裕, 河野 修興, 日和田 邦男) 34/3, 215-220 1997 () 10.3143/geriatrics.34.215

薬剤リンパ球刺激試験が診断に有用であったヘアースプレー肺炎の1例
 分子呼吸器病 () 1/, 373-378 1997 ()

Budd-Chiari症候群による肝硬変に合併した肺高血圧症の一剖検例
 呼吸と循環 () 46/, 1247-1251 1998 () 10.11477/mf.1404910106

カリニ肺炎の診断,モニタリングに誘発痰のPCRが有用であった1例
 分子呼吸器病 () 3/, 134-137 1999 ()

クラリスロマイシンが著効した高齢者Mycobacterium avium complex症の1例
 日本老年医学会雑誌 (浜田泰伸, 河野修興, 横山彰仁, 近藤圭一, 日和田邦男) 37/9, 749-753 2000 () 10.3143/geriatrics.37.749

高齢男性に筋肉内腫瘤を形成したサルコイドーシスの1例
 日本老年医学会雑誌 (青野 潤, 濱田 泰伸, 横山 彰仁, 近藤 圭一, 河野 修興, 日和田 邦男) 38/5, 689-692 2001 () 10.3143/geriatrics.38.689

尿崩症を呈した肺小細胞癌の1例
 日本呼吸器学会雑誌 () 40/, 154-159 2002 ()

Natural killer cells and eicosapentaenoic acid. Proceedings of AOCS Short Course on PUFA and Eicosanoids
 American Oil Chemists' Society () /, 127-132 1987 ()

成人気管支喘息に対するNedocromilの長期投与における有効性,安全性およびステロイド減量効果についての臨床的検討
 臨牀と研究 () 70/, 3964-3971 1993 ()

びまん性汎細気管支炎に刀鞘型気管軟化症を合併した1例
 日本老年医学会雑誌 (池田 俊太郎, 井上 義一, 藤野 俊, 藤岡 精二, 濱田 泰伸, 横山 彰仁, 河野 修興, 日和田 邦男) 30/11, 974-977 1993 () 10.3143/geriatrics.30.974

原発性アルドステロン症の合併が増悪因子と考えられた閉塞型睡眠時無呼吸症候群の1例
 日胸疾会誌 (井上 義一, 伊賀瀬 道也, 大塚 知明, 横山 彰仁, 河野 修興, 日和田 邦男) 32/3, 288-292 1994 () 10.11389/jjrs1963.32.288

ベガ錠投与により,喘鳴が消失した慢性気管支炎に合併した気管支喘息の1例
 現代医療 () 26/, 935-936 1994 ()

胸部X線写真上,連珠状陰影を呈した肺小細胞癌の1例
 日胸疾会誌 (藤野 俊, 河野 修興, 藤岡 精二, 濱田 泰伸, 井上 義一, 横山 彰仁, 日和田 邦男) 33/5, 588-591 1995 () 10.11389/jjrs1963.33.588

経過中に菌種交代を認めたアレルギー型肺アスペルギルス症の1例
 日本胸部疾患学会雑誌 (山本 浩三, 阿部 聖裕, 井上 義一, 横山 彰仁, 河野 修興, 日和田 邦男) 33/10, 1099-1104 1995 () 10.11389/jjrs1963.33.1099

高齢者に発症した腹部脂肪織炎が原因と考えられた両側乳糜胸の1例
 日本老年医学会雑誌 (藤野 俊, 河野 修興, 井上 義一, 藤岡 精二, 濱田 泰伸, 阿部 聖裕, 横山 彰仁, 日和田 邦男) 32/7, 516-519 1995 () 10.3143/geriatrics.32.516

著しい血清CA19-9高値が治療奏功後正常化した気管支拡張症の1例
 日本胸部臨床 () 55/, 312-316 1996 ()

多発性肺動脈瘤と腎血管性高血圧を認めた多発性血管炎オーバーラップ症候群の1例
 日本胸部疾患学会雑誌 (田口 禎一郎, 橋本 明栄, 松田 昌三, 渡辺 誠一郎, 藤野 俊, 井上 義一, 横山 彰仁, 河野 修興, 日和田 邦男) 34/4, 428-433 1996 () 10.11389/jjrs1963.34.428

腎移植後に発症した肺ノカルジア症を合併したリポイド肺炎の1例
 日本胸部疾患学会雑誌 (阿部 聖裕, 近藤 圭一, 藤野 俊, 平澤 泰, 横山 彰仁, 河野 修興, 日和田 邦男) 34/6, 737-740 1996 () 10.11389/jjrs1963.34.737

肺癌患者における電解質異常の臨床的検討
 日胸 () 46/, 363-367 1987 ()

良性呼吸器疾患と肺癌の合併に関する臨床的検討
 臨床と研究 () 63/, 145-147 1988 ()

胸水穿刺115例の臨床的検討
 日胸 () 49/, 135-140 1990 ()

慢性関節リウマチ患者におけるパルミチン酸デキサメサゾン投与後のデキサメサゾン血中濃度
 リウマチ科 () 4/, 585-590 1990 ()

当科における肺結核を合併した肺癌症例の臨床的検討
 日胸 () 50/, 464-468 1991 ()

間質性肺炎における血清トロンボモジュリンの検討
 日胸疾会誌 (横山 彰仁, 河野 修興, 藤岡 精二, 濱田 泰伸, 藤野 俊, 井上 義一, 日和田 邦男) 32/10, 951-955 1994 () 10.11389/jjrs1963.32.951

HTLV-1キャリアーにおける慢性気道感染症の検討?ロキシスロマイシンによる治療効果を含めて?
 Therapeutic Research () 17/, 721-727 1996 ()

気管支喘息治療における短期経口ステロイド使用の現状?四国地区のアンケート結果より?
 呼吸 () 15/, 1450-1457 1996 ()

著明な肺病変を伴ったホジキン病の一例
 日胸疾会誌 (横山 彰仁, 鈴木 英彦, 泉 三郎, 矢野 三郎) 22/8, 703-707 1984 () 10.11389/jjrs1963.22.703

Photo Report:家族性高コレステロール血症(FH)のヘテロ接合体患者にみられた著明なxanthoma
 内科 () 58/, 1178 1996 ()

セフェム系抗生物質が原因として疑われたびまん性肺出血の一例
 日胸疾会誌 (丸山 宗治, 水島 豊, 本 敦文, 山下 直宏, 杉山 英二, 星野 清, 横山 彰仁, 矢野 三郎) 24/3, 316-319 1986 () 10.11389/jjrs1963.24.316

IgG and IgM rheumatoid factor levels parallel interleukin-6 during the vasculitic phase in a patient with Churg-Strauss syndrome
 Intern Med () 34/7, 646-648 1995 () 10.2169/internalmedicine.34.646

Near-Death Asthmatic Reaction Induced by Disodium Cromoglycate
 Intern Med (KATAYAMA H, YOKOYAMA A, FUJINO S, KONDO K, ABE M, NISHIDA W, KOHARA K, KOHNO N, HIWADA K) 35/12, 976-978 1996 () 10.2169/internalmedicine.35.976

Distal acinar emphysema and interstitial pneumonia in a patient with von Recklinghausen’s      disease: Five year observation following quitting smoking
 Intern Med () 36/6, 413-416 1997 () 10.2169/internalmedicine.36.413

KL-6 as a serologic indicator of Pneumocystis carini pneumonia in immunocompromised hosts
 Intern Med () 37/3, 307-310 1998 () 10.2169/internalmedicine.37.307

Severe inclusion body myositis with interstitial pneumonia
 Intern Med () 40/9, 940-944 2001 () 10.2169/internalmedicine.40.940

Humidifier Lung: Possible Contribution of Endotoxin-induced Lung Injury
 Intern Med () 41/12, 1179-1182 2002 () 10.2169/internalmedicine.41.1179

ラットにおけるcisplatin腎毒性の基礎的研究
 医学のあゆみ () 137/, 135-136 1986 ()

当院入院患者からみた内科領域における最近の肺感染症の現状
 臨床と研究 () 63/, 1551-1556 1986 ()

悪性腫瘍の補助診断におけるTPAの有用性
 癌の臨床 () 32/, 779-782 1996 ()

慢性肺疾患患者における右室負荷のタリウム201心筋スキャンによる検討.血液ガスおよび心電図所見との関連性について
 日胸疾会誌 (横山 彰仁, 沢崎 茂樹, 朝日 寿実, 由井 米光, 水島 豊, 山下 直宏, 矢野 三郎) 25/3, 328-333 1987 () 10.11389/jjrs1963.25.328

肺癌診断におけるCEA,TPA combination assayの有用性
 日胸 () 46/, 37-41 1987 ()

A novel monoclonal antibody, H9, directed against the core protein of MUC1 mucin
 Oncol Rep () 7/, 225-232 2000 ()

Eotaxin levels in pleural effusion
 Intern Med () 39/, 547-552 2000 () 10.2169/internalmedicine.39.547

Induced ACTH secretion by allergen inhalation
 J Asthma () 37/, 497-502 2000 ()

Effect of aerosolized docosahexaenoic acid in a mouse model of atopic asthma
 Int Arch Allergy Immunol () 123/, 327-332 2002 () 10.1159/000053645

Decreased E-cadherin augments b-catenin nuclear localization: Studies in breast cancer cell lines
 Int J Oncol () 18/, 541-548 2001 ()

Prolonged antigen exposure ameliorates airway inflammation but not remodeling in a mouse model of bronchial asthma
 Int Arch Allergy Immunol () 126/, 126-134 2001 () 10.1159/000049503

Production of eosinophilic chemokines by normal pleural mesothelial cells
 Am J Respir Cell Mol Biol () 26/, 398-403 2002 ()

Comparative study of KL-6, SP-A, SP-D and MCP-1 as serum markers for interstitial lung diseases
 Am J Respir Crit Care Me () 165/, 378-381 2002 ()

Type 1 helper T cells induce alveolitis but do not lead to pulmonary fibrosis in mice
 Eur Respir J () 21/, 44153 2003 () 10.1183/09031936.03.00291203

Acute eosinophilic pneumonia induced by minocycline: Prominent Kerley-B lines as a feature of positive re-challenge test
 Jpn J Med () 29/2, 195-198 1990 () 10.2169/internalmedicine1962.29.195

Acetaminophen-induced eosinophilic pneumonia
 Chest () 104/, 291-292 1993 ()

Drug eruption caused by recombinant human G-CSF
 Intern Med () 33/, 646-648 1994 ()

Inhibition of thromboxan A2 attenuates antigen-induced pulmonary eosinophilia in mice
 Eur Respir J () 11/, 624-629 1998 ()

Decreased MUC1 expresssion induces E-cadherin-mediated cell adhesion of breast cancer cell lines
 Cancer Re () 58/, 2014-2019 1998 ()

Soluble interleikin-6 receptor in rheumatoid arthritis
 Jpn J Rheum () 8/, 131-138 1998 ()

Diagnostic evaluation of sialylated carbohydrate antigens, KL-6, CA19-9 and SLX as serum markers for interstitial pneumonitis
 Respirology () 3/, 199-202 1998 ()

Circulating KL-6 predicts the outcome of rapidly progressive idiopathic pulmonary fibrosis
 Am J Respir Crit Care Med () 158/, 1680-84 1998 ()

Detection of serum IgE antibody directed to aminothiazole using immobilized cephalosporins without protein conjugation
 Allergol Int () 48/, 303-308 1999 () 10.1046/j.1440-1592.1999.00149.x

Effect of different sensitizing doses of antigen in a murine model of atopic asthma
 Clin Exp Immunol () 118/, 44089 1999 () 10.1046/j.1365-2249.1999.01036.x

Adriamycin activates E-cadherin-mediated cell-cell adhesion in human breast cancer cell lines
 Int J Oncol () 15/, 1109-1115 1999 ()

High serum KL-6 level predicts the deterioration of pulmonary function in patients with rheumatoid arthritis
 Jpn J Rheumatol () 9/, 373-380 1999 ()

Effect of suplatast tosilate (IPD-1151T) on a mouse model of asthma: inhibition of eosinophilic inflammation and bronchial hyperresponsiveness
 Int Arch Allergy Immunol () 121/, 116-122 2000 ()

Natural autoantibody to MUC1 is a prognostic indicator for non-small cell lung cancer
 Am J Respir Crit Care Med () 161/, 589-594 2000 ()

Comparative studies of circulating KL-6, type III procollagen N-terminal peptide and type IV collagen 7S in patients with interstitial pneumonitis and alveolar pneumonia
 Respir Med () 91/, 558-561 1997 () 10.1016/S0954-6111(97)90090-1

KL-6, a human MUC1 mucin, is chemotactic for human fibroblasts
 Am J Respir Cell Mol Biol () 17/, 501-507 1997 ()

Detection of interstitial pneumonitis complicated in patients with rheumatoid arthritis by measuring circulating levels of KL-6, a human MUC1 mucin
 Lung () 175/, 379-385 1997 () 10.1007/PL00007584

Circulating levels of soluble interleukin-6 receptor in patients with bronchial asthma
 Am J Respir Crit Care Med () 156/, 1688-1691 1997 ()

Effect of pranlukast, a leukotriene receptor antagonist, in patients with sever asthma refractory to corticosteroids
 J Asthma () 35/, 57-62 1998 ()

A circulating heat-resistant mucin-like antigen in patients with lung cancer detected by a new murine monoclonal antibody
 Int J Oncol () 1/, 649-655 1992 ()

KL-6, a mucin-like glycoprotein, in bronchoalveolar lavage fluids from patients with interstitial lung disease
 Am Rev Respir Dis (currently Am J Respir Crit Care Med) () 148/, 637-642 1993 ()

Origin of heterogeneity of interleukin-6 (IL-6) levels in malignant pleural effusions
 Oncol Rep () 1/, 507-511 1994 ()

Difference in sero-diagnostic values among KL-6-associated mucins classified as cluster 9
 Int J Cancer () 8/, 81-83 1994 ()

Evaluation of serum KL-6 levels in patients with pulmonary tuberculosis
 Tubercle Lung Dis () 76/, 230-233 1995 ()

Circulating interleukin-6 levels in patients with bronchial asthma
 Am J Respir Crit Care Med () 151/, 1354-1358 1995 ()

Evaluation of soluble interleukin-6 receptor concentration in serum and epithelial lining fluid from patients with interstitial lung diseases
 Clin Exp Immunol () 100/, 325-329 1995 ()

Interleukin-6 is an autocrine growth factor for normal human pleural mesothelial cells
 Am J Respir Cell Mol Biol () 14/, 508-515 1996 ()

Soluble interleukin-6 receptor levels in pleural effusions
 Respir Med () 90/, 329-332 1996 () 10.1016/S0954-6111(96)90127-4

Comparative studies of CAM 123-6 and carcinoembryonic antigen for the serological detection of pulmonary adenocarcinoma
 Cancer Detect Prev () 21/, 124-128 1997 ()

T helper 2 (Th2) but not Th1 clones co-stimulate resting T cells in the presence of anti-CD3 monoclonal antibody
 Int Immunol () 1/, 443-449 1989 ()

Direct activation of murine resting T cells by ConA or anti-CD3 immunogloburin
 J Mol Cell Immunol (currently Immunol Invest) () 4/, 225-237 1989 ()

Inhibition of natural killer cell activity by oral administration of theophylline
 Chest () 98/, 924-927 1990 ()

Delayed antigen presentation by epidermal Langerhans cells to cloned Th1 and Th2 cells
 J Invest Dermatol () 95/, 446-449 1990 ()

Relative contribution of CD2 and LFA-1 to murine T and NK cell functions
 J Immunol () 145/, 3628-3634 1990 ()

Characterization of inhibitory effect of an anti-murine CD2 monoclonal antibody on the proliferation of T cell clones
 Immunol Lett () 28/, 219-226 1991 ()

Interleukin-2-activated murine cell lines with macrophage- and B-lymphoblast-lytic activity
 Cell Immunol (SUZUKI H, IKEMOTO M, YOKOYAMA A, KAMITANI T, YAMASHITA N, MARUYAMA M, YANO S) 132/1, 127-139 1991 () 10.1016/0008-8749(91)90012-Z

Preliminary study on auxiliary value of serum basic fetoprotein in diagnostic lung cancer
 Tumori () 77/, 315-318 1991 ()

Roles for interleukin 2 (IL-2) and IL-4 in the generation
 Experientia () 48/, 281-284 1992 () 10.1007/BF01930476

Interleukin 6 activity in pleural effusion: Its diagnostic value and thrombopoietic activity
 Chest () 102/, 1055-1059 1992 ()

KL-6 as a serum marker for amiodarone-induced pulmonary toxicity
 Intern Med () 39/, 38108 2000 ()

Archives2001基礎編:リンパ球?間質性肺疾患?
 分子呼吸器病 () 5/, 509-511 2001 ()

各論:診断と治療。結核性胸膜炎、膿胸
 化学療法の領域 2001増刊号「結核と非定型抗酸菌症のすべて」 () 17/, 162-167 2001 ()

Prostaglandine E2 inhibits the generation of phytohemagglutinin-activated killer cell activity in human peripheral blood lymphocytes
 Anticancer Res () /, 1113-1116. 1986 ()

Inhibition of natural killer cell activity of human lymphocytes by eicosapentaenoic acid
 Biochem Biophys Res Comm (YAMASHITA N, YOKOYAMA A, HAMAZAKI T, YANO S) 138/3, 1058-1067 1986 () 10.1016/S0006-291X(86)80389-8

Studies on nephrotoxicity following a single and repeated administration of cis-diamminedichloroplatinum (CDDP) in rats
 Tohoku J Exp Med () 151/2, 129-135 1987 () 10.1620/tjem.151.129

The infusion of the icosapentaenoyl-glycerol into humans and the in vivo formation of prostaglandin-I3 and thromboxane A3
 Biochem Biophys Res Comm (HAMAZAKI T, FISCHER S, SCHWEER H, MEESE C O, URAKAZE M, YOKOYAMA A, YANO S) 151/3, 1386-1394 1988 () 10.1016/S0006-291X(88)80516-3

Antigenicity of passively acquired major histocompatibility antigens on T cells
 Transplantation () 46/, 137-143 1988 ()

Production of IL-2 and IFN-g by Th2 clones
 Immunol Lett () 21/, 119-126 1988 ()

薬物による電解質異常
 臨床と研究 () 63/, 468-74 1986 ()

高齢者におけるかぜ症候群および肺炎の治療と予防
 臨床と研究 () 68/, 1715-1718 1991 ()

びまん性肺疾患における血清マ?カ?KL-6の臨床的有用性と今後の展望
 愛媛医学 () 11/, 238-245 1992 ()

胸郭子宮内膜症
 別冊・日本臨牀 領域別症候群シリーズ No. 4呼吸器症候群 () /, 781-784 1994 ()

インターロイキン6
 日本臨牀臨時増刊 「広範囲血液・尿化学検査,免疫学的検査」 () 53/, 790-793 1995 ()

喘息とIL-6
 喘息 () 8/, 29-34 1995 ()

アレルギー疾患におけるリンパ球機能とサイトカイン
 アレルギーの臨床 () 17/, 755-759 1997 ()

KL-6の新しい展開
 分子呼吸器病 () 2/, 230-232 1998 ()

好酸球浸潤に関わるケモカイン
 分子呼吸器病 () 2/, 176-182 1998 ()

動物モデル:気管支喘息
 分子呼吸器病 () 3/, 77-83 1999 ()

インターロイキン6および可溶性インターロイキン6受容体
 日本臨牀臨時増刊 「広範囲血液・尿化学検査, 免疫学的検査(3)」 () 57/, 783-786 1999 ()

気管支喘息のサイトカイン動態と病態
 SRL宝函 () 23/, 263-268 2000 ()

新たな分子標的治療と臨床問題:気管支喘息
 日本内科学会雑誌 () 92/7, 1272-1278 2003 () 10.2169/naika.92.1272

特発性間質性肺炎を伴った肥大型心筋症に対してCibenzolineが有効であった一例
 日本老年医学会雑誌 (齋藤 実, 原 裕二, 重松 裕二, 大塚 知明, 佐伯 秀幸, 大木元 明義, 横山 彰仁, 濱田 希臣) 40/1, 62-64 2003 () 10.3143/geriatrics.40.62

Circulating KL-6 Levels in Patients with Drug-induced Pneumonitis
 Thorax () 58/, 872-5 2003 () 10.1136/thorax.58.10.872

Rapid progression of primary cardiac leiomyosarcoma with obstruction of the left ventricular outflow tract and mitral stenosis
 Internal Medicine (OGIMOTO A, HAMADA M, OHTSUKA T, HARA Y, SHIGEMATSU Y, YOKOYAMA A, IMAGAWA H, KAWACHI K, KITO K) 42/9, 827-830 2003 () 10.2169/internalmedicine.42.827

■ 研究業績(著書)
CD4+T細胞サブセット(Th1,Th2)について(1990)
 出版社:中外医学社/Annual Review免疫1990

薬剤性肺炎(1993)
 出版社:桂書房/研修医のための呼吸器疾患診療マニュアル

薬剤誘起性肺疾患(1993)
 出版社:先端医学社/気管支肺胞洗浄

成人呼吸促迫症候群(1993)
 出版社:先端医学社/気管支肺胞洗浄

インターロイキン6,上皮成長因子,Th1,Th2細胞(1994)
 出版社:先端医学社/KEY WORD 1994-95呼吸器系

サイトカイン(1994)
 出版社:先端医学社/KEY WORD 1994-95循環系

可溶性インターロイキン6レセプター,中皮腫,トロンボモジュリン,ランテス(1996)
 出版社:先端医学社/KEY WORD 1996-97呼吸器系

気管支喘息とインターロイキン6(1997)
 出版社:Excerpta Medica/Asthma-an inflammatory disease vol. 5 「patient education and inhaled steroids」

KL-6: 間質性肺炎の血清マーカー(1999)
 出版社:先端医学社/KEY WORD 1999-2000 呼吸器系

インターロイキン6/可溶性インターロイキン6受容体,エオタキシン(1999)
 出版社:先端医学社/KEY WORD 1999-2000 呼吸器系

Th1,Th2細胞(1999)
 出版社:先端医学社/KEY WORD 1999-2000 呼吸器系

合併症を伴った高血圧患者:気管支喘息,肺気腫(1999)
 出版社:フジメディカル出版/高血圧ガイドブック

呼吸器疾患領域・総論(2000)
 出版社:先端医学社/慢性疾患患者のQOLと看護ケア

呼吸器疾患領域・気管支喘息;肺気腫・慢性気管支炎(2000)
 出版社:先端医学社/慢性疾患患者のQOLと看護ケア

呼吸器疾患の検査(2002)
 出版社:不二出版/臨床検査・21世紀の展望

薬剤性肺炎(2002)
 出版社:メディカルビュー社/「間質性肺炎?びまん性肺疾患」呼吸器病new approach 7

老年者の薬物療法(2003)
 出版社:朝倉書店.&0d0a;「老年医学」

「呼吸器疾患を探る.非腫瘍編」シミュレイション内科。毎日吸ってる?(2003)
 出版社:永井書店

■ 研究業績(口頭・ポスター)

■ 研究業績(特許)

■ 研究業績(その他の活動)


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