■ 氏名
片岡 正典 (カタオカ マサノリ)
KATAOKA Masanori

■ 所属部局/職名
その他/特任講師

■ 学部・学科・コース等
Science Research Center
総合研究センター

■ 連絡先
住 所780-8073高知市朝倉本町2丁目17−47国際・地域連携センター3階
電 話088-888-8016
F A X088-888-8015
E-Mailm.kataoka●kochi-u.ac.jp    (送信の際は“●”を半角の“@”に変更して送信してください。)
U R Lhttp://www.cc.kochi-u.ac.jp/~m.kataoka/

■ 出身大学院・研究科等

■ 出身学校・専攻等

■ 取得学位

■ 研究職歴

■ 委員歴・役員歴

■ 受賞学術賞

■ 所属学会

■ 専門分野
核酸科学
有機合成化学
海洋天然物化学

■ 主な研究テーマ・活動
海洋性天然化合物の探索
機能性人工核酸の合成
天然核酸関連化合物の合成

■ 研究についてのPR

■ 社会人・生徒を対象として可能な講演・授業(例えば講演題目)

■ 研究業績(論文・解説)
リン酸部位を修飾した核酸の合成
 蛋白質・核酸・酵素 (早川芳宏, 広瀬雅朗, 片岡正典) 40/, 124-132 1995 (学術雑誌)

リン酸部修飾オリゴDNAの立体選択的合成
 化学 (早川芳宏, 片岡正典) 50/, 706-707 1995 (学術雑誌)

High Pressure Organic Chemistry; XV. Non-Catalyzed Cleavage Reaction of Ethers with Acyl Halides.
 High Pressure Research (Hiyoshizou Kotsuki, Yoshikatsu Ichikawa, Mitsuhiro Iwasaki, Masanori Kataoka, Hitoshi Nishizawa) 11/, 107-118 1992 (学術雑誌)

High Pressure-Promoted Uncatalyzed Hydrolysis of Epoxides.
 Tetrahedron Lett. (Hiyoshizou Kotsuki, Masanori Kataoka, Hitoshi Nishizawa) 34/, 4031-4034 1993 (学術雑誌)

High Pressure Organic Chemistry. 17. Diels Alder Reaction of Methyl Palustrate with Maleic Anhydride and N-Phenylmaleimide.
 J. Chem. Soc. Perkin Trans. 1 (Hiyoshizou Kotsuki, Masanori Kataoka, Kohtaro Matsuo, Shigeru Suetomo, Hitoshi Nishizawa) /, 2773-2776 1993 (学術雑誌)

High Pressure-Promoted and Silica gel Catalyzed Aminolysis of Epoxides with Glysine Esters.
 Chem. Lett. (Hiyoshizou Kotsuki, Tomoyasu Shimanouchi, Masahiro Teraguchi, Masanori Kataoka, Akira Tatsukawa, Hitoshi Nishizawa) /, 2159-2162 1994 (学術雑誌)

Facile Internucleotide-Bond Formation via the Phosphoramidite Approach Using BF3-benzimidzole Complex as a Promoter.
 Nucleic Acids Symposium Series (Masaaki Hirose, Masanori Kataoka, Ryoji Noyori, Yoshihiro Hayakawa) 31/, 23-24 1994 (学術雑誌)

Catalytic Use of 1H-tetrazole in Condensation of a Nucleoside and a Nucleoside Phosphoramidite.
 Nucleic Acids Symposium Series (Masanori Kataoka, Yoshihiro Hayakawa) 34/, 175-176 1995 (学術雑誌)

Nucleotide Synthesis via the Phosphoramidite Method Using Benzimidazolium Triflate as a Promoter.
 Nucleic Acids Symposium Series (Masanori Kataoka, Yoshihiro Hayakawa) 35/, 69-70 1996 (学術雑誌)

Benzimidazolium Triflate as an Efficient Promoter for Nucleotide Synthesis via the Phosphoramidite Method.
 J. Org. Chem. (Yoshihiro Hayakawa, Masanori Kataoka, Ryoji Noyori) 61/, 7996-7997 1996 (学術雑誌)

Imidazolium Triflate as an Efficient Promoter for O-Selective Phosphitylation of N-Unprotected Nucleosides via the Phosphoramidite Approach.
 Nucleic Acids Symposium Series (Masanori Kataoka, Yoshihiro Hayakawa) 37/, 21-22 1997 (学術雑誌)

Preparation of the Short Oligonucleotides via the Phosphoramidite Method Using a Tetrazole Promoter in a Catalytic Manner.
 J. Am. Chem. Soc. (Yoshihiro Hayakawa, Masanori Kataoka) 119/, 11758-11762 1997 (学術雑誌)

Evidence Supporting the Activity of 2'-C-Cyano-2'-Deoxy-1-β-D-arabino Pentafuranosylcytosine as a Terminator in Enzymatic DNA-Chain Elongation.
 Bioorg. Med. Chem. Lett. (Yoshihiro Hayakawa, Rie Kawai, Kaori Otsuki, Masanori Kataoka, Akira Matsuda) 8/, 2559-2562 1998 (学術雑誌)

Facile Synthesis of Oligodeoxyribonucleotides via the Phosphoramidite Method without Nucloside Base Protection.
 J. Am. Chem. Soc. (Yoshihiro Hayakawa, Masanori Kataoka) 120/, 12395-12401 1998 (学術雑誌)

Synthesis and Stability of 2'-C-Cyano-2'-deoxy-1-β-D-arabino-pentafuranosylcytosinylyl (3'-5')thymidine.
 Nucleic Acids Symposium Series (Rie Kawai, Kaori Otsuki, Masanori Kataoka, Yoshihiro Hayakawa, Akira Matsuda) 39/, 5-6 1998 (学術雑誌)

A Convenient Method for the Synthesis of N-Free 5'-O-(p,p'-Dimethoxytrityl)-2'-deoxyribonucleosides via the 5'-O-Selective Tritylation of the Parent Substances.
 J. Org. Chem. (Masanori Kataoka, Yoshihiro Hayakawa) 64/, 6087-6089 1999 (学術雑誌)

A Facile Solid-Phase Synthesis of Oligodeoxyribonucleotides and Their Amino Acid Conjugates via the Allyl-Protected Phosphoramidite Approach with Benzimidazolium Triflate as a Promoter.
 Collection Symposium Series A. Holy and M. Hocek, Eds (Yoshihiro Hayakawa, Akira Sakakura, Sophie Heidenhain, Masanori Kataoka) 2/, 105-108 1999 (学術雑誌)

A Facile Synthesis of Oligomers with Modified Backbones via the Phosphoramidite Method without Nucleoside Base Protection.
 Nucleic Acids Symposium Series (Masanori Kataoka, Rie Kawai, Yoshihiro Hayakawa) 32/, 105-106 1999 (学術雑誌)

Phosphoramidite Solid-Phase Synthesis of Site-Specifically Glycosylated Oligonucleotides.
 Tetrahedron Lett. (Kazunori Matsuura, Miki Hibino, Masanori Kataoka, Yoshihiro Hayakawa, Kazukiyo Kobayashi) 41/, 7259-7523 2000 (学術雑誌)

An Efficient Synthesis of Nucleotides via the Phosphoramidite Method Using a Triflic Acid Salt of an Imidazole-Related Compound as a Promoter.
 Nucleic Acids Symposium Series (Akira Sakakura, Masanori Kataoka, Rie Kawai, Yoshihiro Hayakawa) 44/, 137-138 2000 (学術雑誌)

Butanone Peroxide as an Efficient Reagent for the Oxidation of Nucleoside Phosphites into Phosphates under Nonbasic Anhydrous Conditions.
 Org. Lett. (Masanori Kataoka, Akira Hattori, Shinya Okino, Mamoru Hyodo, Mitsue Asano, Rie Kawai, Yoshihiro Hayakawa) 3/, 815-818 2001 (学術雑誌)

Efficient Liquid-phase Synthesis of Short-length Nucleotides via the Phosphoramidite Method Using Stoichiometric Amounts of Reactants.
 Nucleic Acids Symposium Series (Akiyoshi Hirata, Jun-ichiro Sugimoto, Rie Kawai, Masanori Kataoka, Yoshihiro Hayakawa) 34/, 215-216 2001 (学術雑誌)

Effect of Molecular Sieves in the Liquid-Phase Synthesis of Nucleotides via the Phosphoramidite Method.
 Tetrahedron (Yoshihiro Hayakawa, Akiyoshi Hirata, Jun-ichiro Sugimoto, Rie Kawai, Akira Sakakura, Masanori Kataoka) 57/, 8823-8826 2001 (学術雑誌)

Acid/Azole Complexes as Highly Effective Promoters in the Synthesis of DNA and RNA Oligomers via the Phosphoramidite Method.
 J. Am. Chem. Soc. (Yoshihiro Hayakawa, Rie Kawai, Akiyoshi Hirata, Jun-ichiro Sugimoto, Masanori Kataoka, Akira Sakakura, Masaaki Hirose, Ryoji Noyori) 123/, 8165-8176 2001 (学術雑誌)

N-Phenylimidazolium Triflate as a Highly Effective Promoter for the Interribonucleotide-Bond Formation via the Phosphoramidite Method.
 Nucleosides, Nucleotides & Nucleic Acids (Rie Kawai, Jun-ichiro Sugimoto, Masanori Kataoka, Yoshihiro Hayakawa) 20/, 1047-1048 2001 (学術雑誌)

Utility of Porous Glass with a New Long-Chain Alkylamine Spacer Arm as a Solid Support for Synthesis of Oligonucleotides via the Phosphoramidite Method.
 Nucleic Acids Res. Suppl (Rie Kawai, Synya Okino, Masanori Kataoka, Eri Kambe, Yoshihiro Hayakawa) 2/, 165-166 2002 (学術雑誌)

The First Asymmetric Synthesis of Trialkyl Phosphates on the Basis of Dynamic Kinetic Resolution in the Phosphite Method Using a Chiral Source in a Catalytic Manner.
 Chem. Comm. (Yoshihiro Hayakawa, Mamoru Hyodo, Kazutaka Kimura, Masanori Kataoka) 2/, 1704-1705 2003 (学術雑誌)

Internucleotide-linkage Formation via the Phosphoramidite Method using a Carboxylic Aicd as a Promoter.
 Nucleic Acids Symposium Ser. (Masayuki Tsukamoto, E. J. Nurminen, Toshihiro Iwase, Masanori Kataoka, Yoshihiro Hayakawa) 48/, 25-26 2004 (学術雑誌)

Bis[3-(triethoxysilyl)propyl]tetrasulfide: the First Liquid Sulfur-transferring Agent Useful for Conversion of Nucleoside Phosphites to the Phosphorothioates.
 Tetrahedron (Mamoru Hyodo, Yumi Sato, Satoko Yamashita, Akira Hattori, Eri Kambe, Masanori Kataoka, Yoshihiro Hayakawa) 61/, 965-970 2005 (学術雑誌)

Carboxylic acids as romoters for internucleotide-bond formation via condensation of a nucleoside phosphoramidite and a nucleoside:relationship between the acidity and the activity of the promoter.
 Tetrahedron (Yoshihiro Hayakawa, Toshiyuki Iwase, E. J. Nurminen, Masayuki Tsukamoto, Masanori Kataoka) 61/, 2203-2209 2005 (学術雑誌)

Pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone as a Novel Universal Base.
 Nucleic Acids Symposium Ser. (Masanori Kataoka, Taisuke Hirano, Kenji Kuroda and Yoshihiro Hayakawa) 49/, 121-122 2005 (学術雑誌)

Synthesis of a Peptide Nucleic Acid Oligomer with Pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone as a Nucleobase.
 Nucleic Acids Symposium Ser. (Masanori Kataoka, Taisuke Hirano, Kenji Kuroda and Yoshihiro Hayakawa) 49/, 123-124 2005 (学術雑誌)

Utility of Azonium Triflates as Promoters for the Condensation of a Nucleoside Phosphoramidite and a Mucleoside in the Agrawal.
 Eu. J. Org. Chem. (Mamoru Hyodo, Hirotaka Ando, Hisashi Nishitani, Akira Hatori, Hiroyuki Hayakawa, Masanori Kataoka, Yoshihiro Hayakawa) /, 5216-5223 2005 (学術雑誌)

A Ribonucleoside with Pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone as a Nucleobase, which Universally Binds to Natural Nucleosides
 Nucleic Acids Symposium Ser. (Kenji Kuroda, Hidehiko Kodama, Masanori Kataoka, and Yoshihiro Hayakawa) 50/, 17-18 2006 (学術雑誌)

Binding Affinity of a Peptide-nucleic Acid Containing Pyrimido[4,5-d]-pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone as a Nucleobase for Oligonucleotide.
 Nucleic Acids Symposium Ser. (Taisuke Hirano, Kenji Kuroda, Masanori Kataoka and Yoshihiro Hayakawa) 51/, 257-258 2007 (学術雑誌)

Preparation of an Artificial Ribonucleoside with pyrimido[4,5-d]pyrimidine-2,4,5,7-(1H,3H,6H,8H)-tetraone as a Base and its Discriminating Ability for Natural Nucleosides.
 Letters in Organic Chemistry (Taisuke Hirano, Kenji Kuroda, Hidehiko Kodama, Masanori Kataoka, Yoshihiro Hayakawa) 4/, 530-534 2007 (学術雑誌)

Peptide-nucleic acids (PNAs) with pyrimido[4,5-d]-pyrimidine-2,4,5,7-(1H,3H,6H,8H) tetraone as a universal base: their synthesis and binding affinity for oligodeoxyribonucleotides.
 Organic & Biomolecular Chemistry (Taisuke Hirano, Kenji Kuroda, Masanori Kataoka & Yosihiro Hayakawa) 7/, 2905-2911 2009 (学術雑誌)

Nucleotide Synthesis via Methods without Nucleoside-base Protection.
 Eur. J. Pharm. Sci. (Yoshihiro Hayakawa, Rie Kawai, Masanori Kataoka) 13/, 5-16 2001 (その他)

■ 研究業績(著書)

■ 研究業績(口頭・ポスター)

■ 研究業績(特許)
マレオパラストリン酸類およびその製造法
 特許平5-62748

三フッ化ホウ素配位化合物およびオリゴヌクレオチドの合成方法
 特許平7-129683

新規複合体およびオリゴヌクレオチドの合成法
 特許平8-230733

オリゴヌクレオチドの化学合成法
 特願平9-241292

5
 特願平11-7094

ユニバーサル塩基
 特願2005-248585

ユニバーサル塩基含有ポリマー
 特願2005-248586

ユニバーサル塩基
 PCT/JP2006/314834

ユニバーサル塩基含有ポリマー
 PCT/JP2006/316585

核酸塩基置換修飾法、核酸塩基選択的置換修飾法及び核酸塩基置換修飾体
 特願2007-207083

修飾ポリヌクレオチド及びその製法
 特願2007-233592

架台ユニット、組み立て架台および脚柱付き組み立て架台
 特願2007-158869

核酸塩基修飾法及び核酸塩基修飾体
 PCT/JP2008/064619

■ 研究業績(その他の活動)


前ページへ戻る