■ 氏名
福島 敦樹 (フクシマ アツキ)
FUKUSHIMA Atsuki

■ 所属部局/職名
Research and Education Faculty, Medical Sciences Cluster, Clinical Medicine Unit/Professor
教育研究部 医療学系 臨床医学部門/教授

■ 学部・学科・コース等
Medical School, Medical Course, Department of Ophthalmology and Visual Science
医学部 医学科 眼科学

■ 連絡先
住 所
電 話088-880-2391
F A X
E-Mailfukusima●kochi-u.ac.jp    (送信の際は“●”を半角の“@”に変更して送信してください。)
U R Lhttp://www.kochi-ms.ac.jp/~fm_ophth/index.htm

■ 出身大学院・研究科等
高知医科大学 博士(医学研究科 免疫学) 1994 ()

■ 出身学校・専攻等
高知医科大学 (医学部 医学科) 1990 ()

■ 取得学位
博士(医学) (課程)

■ 研究職歴
1996- 高知医科大学眼科 助手
2004- 高知大学医学部眼科 助教授
2008- 高知大学医学部眼科 教授

■ 委員歴・役員歴
日本眼炎症学会 理事
日本眼科アレルギー研究会 理事

■ 受賞学術賞
ARVO American Uveitis Society Travel Fellowship (1996) 国外
4th International Uveitis Travel Fellowship (1997) 国外
赤木賞 高知信用金庫安心友の会学術奨励賞 (1998)
第11回小林孫兵衛記念医学振興財団研究助成 (2003)
第1回日本眼炎症学会学術奨励賞 (2003)
平成15年度日本眼科学会学術奨励賞 (2003)
第11回ロートアワード (2005)
第3回日本アレルギー学会学術大会賞 (2007)

■ 所属学会
日本眼科学会
 ( 国内)
日本免疫学会
 ( 国内)
ARVO(Association of Research for Vision & Ophthalnology)
 ( 国外)
日本アレルギー学会
 ( 国内)
日本眼炎症学会
 ( 国内)

■ 専門分野
眼科学,免疫学

■ 主な研究テーマ・活動
眼炎症疾患とくにT細胞が関与する疾患(ぶどう膜炎,アレルギー性結膜疾患)の発症機構の解明

■ 研究についてのPR
動物実験モデルを用いた解析を行っており,種々の薬効評価ができる

■ 社会人・生徒を対象として可能な講演・授業(例えば講演題目)
ぶどう膜炎とアレルギー性結膜疾患

■ 研究業績(論文・解説)
Image analyses of the kinetic changes of conjunctival hyperemia in histamine-induced conjunctivitis in guinea pigs.
 Cornea (Fukushima A, Tomita T. ) 28/6, 694-698 2009 (学術雑誌)

Ablation of type I hypersensitivity in experimental allergic conjunctivitis by eotaxin-1/CCR3 blockade
 Int Immunol (Miyazaki D, Nakamura T, Ohbayashi M, Kuo CH, Komatsu N, Yakura K, Tominaga T, Inoue Y, Higashi H, Murata M, Takeda S, Fukushima A, Liu FT, Rothenberg ME, Ono SJ) /, in press (学術雑誌)

MHC-matched corneal allograft rejection in an IFN-gamma/IL-17-independent manner in C57BL/6 mice
 Invest Ophthalmol Vis Sci (Yamada J, Hamuro J, Fukushima A, Ohteki T, Terai K, Iwakura Y, Yagita H, Kinoshita S) /, in press (学術雑誌)

Notch ligand Delta-like4 inhibits the development of murine experimental allergic conjunctivitis
 Immunol Letters (Fukushima A, Sumi T, Ishida W, Ojima A, Kajisako M, Koyanagi A, Koyama N, Yagita H  (corresponding author)) 121/, 140-147 2008 (学術雑誌)

Treatment with FTY720 during the induction or effector phase suppresses the development of experimental allergic conjunctivitis in mice
 Cell Biol Int (Sumi T, Fukushima A, Nishino K, Fukuda K, Kumagai N, Nishida T, Ueno H (corresponding author)) /, in press (学術雑誌)

Activation of tumor necrosis factor-related apoptosis-inducing ligand receptor enhances the severity of murine allergic conjunctivitis
 Br J Ophthalmol (Sumi T, Ishida W, Okumura K, Yagita H, Fukushima A (corresponding author)) 93/, 110-115 2009 (学術雑誌)

CD27 and CD70 do not play a critical role in the development of experimental allergic conjunctivitis in mice
 Immunol Letters (Sumi T, Ishida W, Ojima A, Kajisako M, Sakanishi T, Yagita H, Fukushima A (corresponding author)) 119/, 91-6 2008 (学術雑誌)

Endogenous IL-17 does not play a significant role in the development of experimental murine allergic conjunctivitis
 Int Arch Allergy Immunol (Fukushima A, Sumi T, Ishida W, Yamada J, Iwakura Y, Ueno H (corresponding author)) 147/, 206-212 2008 (学術雑誌)

Depletion of thymus-derived CD4+CD25+ T cells abrogates the suppressive effects of alpha-galactosylceramide treatment on experimental allergic conjunctivitis
 Allergol Int (Fukushima A, Sumi T, Ishida W, Ojima A, Kajisako M, Ueno H, Taguchi O (corresponding author)) 57/, 241-6 2008 (学術雑誌)

The Effect of a Combined Therapy with a Histamine H1 Antagonist and a Chemical Mediator Release Inhibitor on Allergic Conjunctivitis
 Ophthalmologica (Fujishima H, Fukagawa K, Tanaka M, Uchio E, Takamura E, Nakagawa Y, Miyazaki D, Fukushima A, Okamoto S, Yokoi N) 222/, 232-239 2008 (学術雑誌)

Roles of galectin-9 in the development of experimental allergic conjunctivitis in mice
 Int Arch Allergy Immunol (Fukushima A, Sumi T, Fukuda K, Kumagai N, Nishida T, Okumura K, Akiba H, Yagita H, Ueno H (corresponding author)) 146/, 36-43 2008 (学術雑誌)

Regulatory T cells participate in 4-1BB-mediated suppression of experimental allergic conjunctivitis
 Int Arch Allergy Immunol (Sumi T, Ishida W, Mittler RS, Yagita H, Taguchi O, Fukushima A (corresponding author)) 148/, 305-310 2008 (学術雑誌)

Intraocular pressure elevation after intravitreal or posterior sub-Tenon triamcinolone acetonide injection
 Can J Ophthalmol (Yamamoto Y, Komatsu T, Koura Y, Nishino K, Fukushima A, Ueno H) 43/, 42-47 2008 (学術雑誌)

Therapeutic effects and mechanisms of action of cyclosporine A ophthalmic solution in the treatment of vernal keratoconjunctivitis
 Curr Pharmaceutical Analysis (Shii D, Fukushima A (corresponding author)) 3/, 213-220 2007 (学術雑誌)

Roles of T cells in the development of allergic conjunctival diseases
 Cornea (Fukushima A (corresponding author)) 26 (Suppl 1)/, S36-S40 2007 (学術雑誌)

Differential contributions of B7-1 and B7-2 to the development of murine experimental allergic conjunctivitis
 Immunol Letters (Sumi T, Fukushima A, Fukuda K, Kumagai N, Nishida T, Yagita H, Ueno H (corresponding author)) 108/, 62-67 2007 (学術雑誌)

Antibodies to T-cell Ig and mucin domain-containing proteins (Tim)-1 and -3 suppress the induction and progression of murine allergic conjunctivitis
 Biochem Biophys Res Commun (Fukushima A, Sumi T, Fukuda K, Kumagai N, Nishida T, Akiba H, Okumura K, Yagita H, Ueno H (corresponding author)) 353/, 211-216 2007 (学術雑誌)

Vogt-Koyanagi-Harada disease with onset in elderly patients aged 68 to 89 years old
 Jpn J Ophthalmol (Yamamoto Y, Fukushima A, Nishino K, Koura Y, Komatsu T, Ueno H (corresponding author)) 51/, 60-63 2007 (学術雑誌)

Thymus-derived CD4+ CD25+ T cells suppress the development of murine allergic conjunctivitis
 Int Arch Allergy Immunol (Sumi T, Fukushima A, Fukuda K, Kumagai N, Nishida T, Takeuchi M, Taguchi O, Ueno H (corresponding author)) 143/, 276-281 2007 (学術雑誌)

Roles of CD4+CD25+ T cells in the development of experimental murine allergic conjunctivitis
 Graefe’s Arch Clin Exp Ophthalmol (Fukushima A, Yamaguchi T, Sumi T, Fukuda K, Kumagai N, Nishida T, Takeuchi M, Taguchi O, Ueno, H (corresponding author)) 245/, 705-714 2007 (学術雑誌)

Endogenous IL-10 produced by Ag-irrelevant cells promotes the development of experimental murine allergic conjunctivitis
 Int Arch Allergy Immunol (Fukushima A, Sumi T, Fukuda K, Kumagai N, Nishida T, Ueno H (corresponding author)) 144/, 79-84 2007 (学術雑誌)

T-cell Ig and mucin domain-containing protein (Tim)-2 regulates murine allergic conjunctivitis during the effector phase
 Immunol Letters (Fukushima A, Sumi T, Fukuda K, Kumagai N, Nishida T, Okumura K, Akiba H, Yagita H, Ueno H (corresponding author)) 110/, 133-138 2007 (学術雑誌)

Cryptomeria japonica-induced allergic conjunctivitis in mice
 Biol Pharm Bull (Fukushima A, Shii D, Sumi T, Kageyama T, Ueno H (corresponding author)) 30/, 1745-1747 2007 (学術雑誌)

B7-H3 regulates the development of experimental allergic conjunctivitis in mice
 Immunol Letters (Fukushima A, Sumi T, Fukuda K, Kumagai N, Nishida T, Yamazaki T, Akiba H, Okumura K, Yagita H, Ueno H (corresponding author)) 113/, 52-57 2007 (学術雑誌)

Role of suppressor of cytokine signaling (SOCS) in ocular allergy
 Curr Opin Allergy Clin Immunol (Kubo M, Ozaki A, Tanaka S, Okamoto M, Fukushima A) 6/, 361-366 2006 (学術雑誌)

TLR2 agonist ameliorates murine experimental allergic conjunctivitis by inducing CD4 positive T-cell apoptosis rather than by affecting the Th1/Th2 balance
 Biochem Biophys Res Commun (Fukushima A, Yamaguchi T, Ishida W, Fukata K, Ueno H (corresponding author)) 339/, 1048-1055 2006 (学術雑誌)

Roles of OX40 in the development of murine experimental allergic conjunctivitis: exacerbation and attenuation of eosniophil infiltration by stimulation and blocking of OX40
 Invest Ophthalmol Vis Sci (Fukushima A, Yamaguchi T, Ishida W, Fukata K, Yagita H, Ueno H (corresponding author)) 47/, 657-663 2006 (学術雑誌)

Liu F-T, Ueno H. Genetic background determines susceptibility to experimental immune-mediated blepharoconjunctivitis: Comparison of Balb/c and C57BL/6 mice
 Exp Eye Res (Fukushima A, Yamaguchi T, Ishida W, Fukata K, Taniguchi T (corresponding author)) 82/, 210-218 2006 (学術雑誌)

Absence of Chlamydia psittaci in ocular adnexal lymphoma from Japanese patients
 Br J Haematol (Daibata M, Nemoto Y, Togitani K, Fukushima A, Ueno H, Ouchi K, Fukushi H, Imai S, Taguchi H) 132/, 651-652 2006 (学術雑誌)

Role of VLA-4 in the development of allergic conjunctivitis in mice
 Mol Vision (Fukushima A, Yamaguchi T, Ishida W, Fukata K, Ueno H (corresponding author)) 12/, 310-317 2006 (学術雑誌)

Inflammatory reaction following cataract surgery and implantation of acrylic intraocular lens in rabbits with endotoxin-induced uveitis
 Eye (Koura Y, Fukushima A, Nishino K, Ishida W, Nakakuki T, Sento M, Yamazoe K, Yamaguchi T, Miyoshi T, Ueno H (corresponding author)) 20/, 606‐610 2006 (学術雑誌)

Lck couples Shc to TCR signaling
 Cell Signal (Fukushima A, Chang J-W, Hatanaka Y, Takamatsu M, Singh N, Iwashima M) 18/, 1182-1189 2006 (学術雑誌)

Liu F-T , Ueno H. Cyclosporin A inhibits eosinophilic infiltration into the conjunctiva mediated by type IV allergic reactions
 Clin Exp Ophthalmol (Fukushima A, Yamaguchi T, Ishida W, Fukata K (corresponding author)) 34/, 347-353 2006 (学術雑誌)

A case of tamoxifen keratopathy
 Arch Ophthalmol (Zinchuk O, Watanabe M, Hayashi N, Fukushima A, Ueno H) 124/, 1046-1048 2006 (学術雑誌)

Involvement of programmed death-ligand 2 (PD-L2) in the development of experimental allergic conjunctivitis in mice
 Br J Ophthalmol (Fukushima A, Yamaguchi T, Azuma M, Yagita H, Ueno H (corresponding author)) 90/, 1040-1045 2006 (学術雑誌)

CD8+ T cells play disparate roles in the induction and the effector phases of murine experimental allergic conjunctivitis
 Microbiol Immunol (Fukushima A, Yamaguchi T, Fukuda K, Sumi T, Kumagai N, Nishida T, Imai S, Ueno H (corresponding author)) 50/, 719-728 2006 (学術雑誌)

The early efficacy of topical levocabastine in patients with allergic conjunctivitis
 Allergol Int (Fujishima H, Fukagawa K, Takano Y, Okamoto S, Nakagawa Y, Uchio E, Yokoi N, Fukushima A, Takamura E) 55/, 301-303 2006 (学術雑誌)

Modulation of murine experimental allergic conjunctivitis by treatment with alpha-Galactosylceramide
 Immunol Letters (Fukushima A, Sumi T, Fukuda K, Yamaguchi T, Kumagai N, Nishida T, Ueno H (corresponding author)) 107/, 32-40 2006 (学術雑誌)

Pharmacokinetic analysis of platelet-activating factor in the tears of guinea pigs with allergic conjunctivitis
 J Ocul Pharmacol Ther (Okumura N, Fukushima A, Igarashi A, Sumi T, Yamagishi T, Ueno H (corresponding author)) 22/, 347-352 2006 (学術雑誌)

IL-10 and TGF-beta contribute to the development of experimentally-induced allergic conjunctivitis in mice during the effector phase
 Br. J. Ophthalmol (Fukushima A, Sumi T, Fukuda K, Kumagai N, Nishida T, Yagita H, Ueno H (corresponding author)) 90/, 1535-1541 2006 (学術雑誌)

Analysis of the interaction between IFN-gamma and IFN-gammaR in the effector phase of experimental murine allergic conjunctivitis
 Immunol Letters (Fukushima A, Sumi T, Fukuda K, Kumagai N, Nishida T, Tsuru E, Ueno H (corresponding author)) 107/, 119-124 2006 (学術雑誌)

Pharmaceutical and histopathological analyses of the developing mechanism of severe allergic conjunctival diseases using experimental animal models: Roles of systemic and local cytokines
 Curr Pharmaceutical Analysis (Fukushima A) 1/, 85-91 2005 (学術雑誌)

Methylation Analysis of the Adenomatous Polyposis Coli (APC) Gene in Adult T-Cell Leukemia/Lymphoma
 Leuk Res (Yang Y, Takeuchi S, Tsukasaki K, Yamada Y, Hata T, Mori N, Fukushima A, Seo H, Koeffler HP, Taguchi H) 29/, 47-51 2005 (学術雑誌)

IkB-alpha-specific transcript regulation by the C-terminal end of c-Rel
 FEBS Letters (Iwai K, Lee BR, Hashiguchi M, Fukushima A, Iwashima M) 579/, 141-144 2005 (学術雑誌)

Systemic interferon (IFN)-gamma suppresses the development of endotoxin-induced uveitis in mice
 Curr Eye Res (Fukushima A, Ozaki A, Ishida W, Fukata K, Ueno H (corresponding author)) 30/, 7-12 2005 (学術雑誌)

Direct action of platelet activating factor (PAF) induces eosinophil accumulation and enhances expression of PAF receptors in conjunctivitis
 Mol Vision (Zinchuk O, Fukushima A, Zinchuk V, Fukata K, Ueno H) 11/, 114-123 2005 (学術雑誌)

Interleukin-4-mediated infiltration of eosinophils into the conjunctiva and its suppression by interferon-gamma
 Curr Eye Res (Fukushima A, Jian Z, Ishida W, Fukata K, Ozaki A, Ueno H (corresponding author)) 30/, 115-122 2005 (学術雑誌)

Liu F-T, Ueno H. Dissection of antigen-specific humoral and cellular immune responses for the development of experimental immune-mediated blepharoconjunctivitis (EC) in C57BL/6 mice
 Curr Eye Res (Fukushima A, Ozaki A, Jian Z, Ishida W, Fukata K (corresponding author)) 30/, 241-248 2005 (学術雑誌)

Suppression of macrophage infiltration into the conjunctiva by clodronate liposomes in experimental immune-mediated blepharoconjunctivitis
 Cell Biol Int (Fukushima A, Ozaki A, Ishida W, van Rooijen N, Fukata K, Ueno H (corresponding author)) 29/, 277-286 2005 (学術雑誌)

Mice lacking the IFN-gamma receptor or fyn develop severe experimental autoimmune uveoretinitis (EAU) characterized by different immune responses
 Immunogenetics (Fukushima A, Yamaguchi T, Ishida W, Fukata K, Udaka K, Ueno H (corresponding author)) 57/, 337-43 2005 (学術雑誌)

The immunization protocol determines whether endogenous interferon-gamma suppresses the infiltration of eosinophils into the conjunctiva
 Immunol Letters (Fukushima A, Yamaguchi T, Ishida W, Fukata K, Ozaki A, Ueno H (corresponding author)) 100/, 189-194 2005 (学術雑誌)

Engagement of 4-1BB inhibits the development of experimental allergic conjunctivitis in mice
 J Immunol (Fukushima A, Yamaguchi T, Ishida W, Fukata K, Mittler RS, Yagita H, Ueno H (corresponding author)) 175/, 4897-4903 2005 (学術雑誌)

The control of allergic conjunctivitis by suppressor of cytokine signaling (SOCS) 3 and SOCS5 in a murine model
 J Immunol (Ozaki A, Seki Y, Fukushima A, Kubo M) 175/, 5489-5497 2005 (学術雑誌)

Fyn regulates eosinophil infiltration into the conjunctiva by downregulating the Th2 response
 Graefe’s Arch Clin Exp Ophthalmol (Fukushima A, Yamaguchi T, Ozaki A, Taniguchi T, Udaka K, Ueno H (corresponding author)) 243/, 1043-1049 2005 (学術雑誌)

Platelet-activating factor species in human tears
 Curr Eye Res (Okumura N, Kojima K, Hashida M, Koura Y, Fukushima A, Ueno H (corresponding author)) 30/, 891-896 2005 (学術雑誌)

The interaction between ICOS and B7RP-1 is not required for the development of experimental murine allergic conjunctivitis
 Biochem Biophys Res Commun (Fukushima A, Yamaguchi T, Ishida W, Fukata K, Yagita H, Ueno H (corresponding author)) 338/, 1726-1731 2005 (学術雑誌)

Role of IL-27-producing dendritic cells in Th1-immunity polarization in Lewis rats
 Biochem Biophys Res Commun (Saito F, Ohno Y, Morisawa K, Kamakura M, Fukushima A, Taniguchi T) 338/, 1773-1778 2005 (学術雑誌)

Detection of antigen-specific T cells in experimental immune-mediated blepharoconjunctivitis in DO11.10 T cell receptor transgenic mice
 Microbiol Immunol (Ozaki A, Ishida W, Fukata K, Fukushima A, Ueno H (corresponding author)) 48/, 39-48 2004 (学術雑誌)

Dynamics of PAF-induced conjunctivitis reveals differential expression of PAF receptor by macrophages and eosinophils in the rat
 Cell Tissue Res (Zinchuk O, Fukushima A, Hangsterfer E, Ueno H) 317/, 265-277 2004 (学術雑誌)

Phenotypic changes and inflammatory cell distribution in the cornea during development of experimental immune-mediated blepharoconjunctivitis
 Jpn J Ophthalmol (Ozaki A, Ishida W, Fukata K, Fukushima A, Ueno H (corresponding author)) 48/, 333-339 2004 (学術雑誌)

Artificial tears inhibit the development of experimental immune-mediated blepharoconjunctivitis
 Jpn J Ophthalmol (Fukushima A, Zinchuk O, Ueno H (corresponding author)) 48/, 530-534 2004 (学術雑誌)

Analysis of Ag-presenting cells in the conjunctiva during the development of experimental immune-mediated blepharoconjunctivitis
 Curr Eye Res (Ozaki A, Fukushima A, Ishida W, Zinchuk O, Fukata K, Hayashi Y, Enzan H, Takata M, Yagita H, Ueno H (corresponding author)) 29/, 277-86 2004 (学術雑誌)

Suppression or exacerbation of experimental autoimmune uveoretinitis in Lewis rats by pretreatment with and without an autoantigenic peptide in aluminum hydroxide
 Jpn J Ophthalmol (Ozaki A, Fukata K, Fukushima A, Yasuoka M, Yoshida O, Ueno H (corresponding author)) 47/, 102-106 2003 (学術雑誌)

Retinal S-Ag reactive lymphocytes in a patient with uveitis associated with myelodysplastic syndromes
 Jpn J Ophthalmol (Nishino K, Fukushima A, Ueno H (corresponding author)) 47/, 265-267 2003 (学術雑誌)

A case of cat scratch disease neuroretinitis confirmed by polymerase chain reaction
 Jpn J Ophthalmol (Fukushima A, Yasuoka M, Tsukahara M, Ueno H (corresponding author)) 47/, 405-408 2003 (学術雑誌)

Mast-cell activation augments the late phase reaction in experimental immune-mediated blepharoconjunctivitis
 Graefe’s Arch Clin Exp Ophthalmol (Ozaki A, Fukushima A, Fukata K, Ueno H (corresponding author)) 241/, 394-402 2003 (学術雑誌)

A novel ERK dependent signaling process that regulates IL-2 expression in a late phase of T cell activation
 J Biol Chem (Koike T, Yamagishi H, Hatanaka Y, Fukushima A, Chan JW, Xia Y, Fields M, Chandler P, Iwashima M) 278/, 15685‐15692 2003 (学術雑誌)

Identification of a new GLC1A mutation in a sporadic, primary open-angle glaucoma in Japan
 Int J Mol Med (Ikezoe T, Takeuchi S, Komatsu N, Okada M, Fukushima A, Ueno H, Koeffler HP, Taguchi H) 12/, 259-261 2003 (学術雑誌)

Ag-specific recognition, activation and effector function of T cells in the conjunctiva with experimental immune-mediated blepharoconjunctivitis
 Invest Ophthalmol Vis Sci (Fukushima A, Ozaki A, Fukata K, Ishida W, Ueno H (corresponding author)) 44/, 4366-4374 2003 (学術雑誌)

Differential expression and signaling of IFN-gamma in the conjunctiva between Lewis and Brown Norway rats
 Microbiol Immunol (Fukushima A, Ozaki A, Fukata K, Ueno H (corresponding author)) 47/, 785-796 2003 (学術雑誌)

Suppression of experimental immune-mediated blepharoconjunctivitis in Brown Norway rats by topical application of FK506
 Graefe’s Arch Clin Exp Ophthalmol (Nishino K, Fukushima A, Okamoto S, Ohashi Y, Fukata K, Ozaki A, Ueno H (corresponding author)) 240/, 137-143 2002 (学術雑誌)

Exertion of the suppressive effects of IFN-gamma on experimental immune-mediated blepharoconjunctivitis in Brown Norway rats during the induction phase but not the effector phase
 Br J Ophthalmol (Fukushima A, Fukata K, Ozaki A, Takata M, Kuroda N, Enzan H, Ueno H (corresponding author)) 86/, 1166-71 2002 (学術雑誌)

Genetic background determines sensitivity to the inhibitory function of NO on T cell proliferation and the amounts of NO production mediated through IFN-gamma
 Microbiol Immunol (Ozaki A, Fukushima A, Fukata K, Sakamoto S, Taniguchi T, Hashiguchi M, Ueno H (corresponding author)) 46/, 555-563 2002 (学術雑誌)

Immunohistochemical study of epiretinal proliferative cellular tissue from a patient with sarcoidosis
 Jpn J Ophthalmol (Fukushima A, Hashida M, Hayashi N, Hiroi, M, Ueno H (corresponding author)) 46/, 675-678 2002 (学術雑誌)

Skewed abrogation of tolerance to a neo self-antigen in double-transgenic mice coexpressing the antigen with interleukin-1beta or interferon-gamma
 Cell Immunol (Zhang M, Fukushima A, Vistica BP, Kim SJ, Hung L, Wawrousek EF, Egwuagu CE, Lee RS, Whitcup SM, Gery I (equally contributed as the first author)) 207/, 6-12 2001 (学術雑誌)

Mechanism for maintenance of dominant T helper 1 immune responses in Lewis rats
 Microbiol Immunol (Sakamoto S, Fukushima A, Ozaki A, Ueno H, Kamakura M, Taniguchi T (corresponding author)) 45/, 373-81 2001 (学術雑誌)

A giant cell angiofibroma involving 6q
 Cancer Genet Cytogenet (Sonobe H, Iwata J, Komatsu T, Fukushima A, Hayashi N, Moriki T, Shimizu K, Ohtsuki Y) 116/, 47-49 2000 (学術雑誌)

The role of IL-12 in the induction of late-phase cellular infiltration in a murine model of allergic conjunctivitis
 J Allergy Clin Immunol (Magone MT, Whitcup SM, Fukushima A, Chan C-C, Silver PB, Rizzo LV) 105/, 299-308 2000 (学術雑誌)

Involvement of superoxide generated by polymorphonuclear leukocytes in endotoxin-induced uveitis
 Graefe’s Arch Clin Exp Ophthalmol (Hashida M, Fukushima A, Zhang J, Kodama H, Ueno H (corresponding author)) 238/, 359-365 2000 (学術雑誌)

Experimental immune-mediated blepharoconjunctivitis (EC) in rats induced by immunization with ragweed pollen (RW)
 Graefe’s Arch Clin Exp Ophthalmol (Iwamoto H, Nishino K, Magone TM, Whitcup SM, Yoshida O, Yoshida H, Ozaki A, Fukushima A, Ueno H (corresponding author)) 238/, 346-351 2000 (学術雑誌)

Analysis of responses of peripheral blood lymphocytes from sarcoidosis patients against purified protein derivative
 Jpn J Ophthalmol (Nishino K, Yoshida H, Yoshida O, Watanabe M, Fukushima A, Ueno H (corresponding author)) 44/, 65-170 2000 (学術雑誌)

Breakdown of tolerance to a neo-self Ag in double transgenic mice in which B-cells present the Ag
 J Immunol (de Vos AF, Fukushima A, Lobanoff MC, Vistica BP, Lai JC, Grivel J-C, Wawrousek EF, Whitcup SM, Gery I) 164/, 4594-4600 2000 (学術雑誌)

Indocyanine green angiographic findings in three patients with traumatic hypotony maculopathy
 Jpn J Ophthalmol (Masaoka N, Sawada K, Komatsu T, Fukushima A, Ueno H) 44/, 283-289 2000 (学術雑誌)

Comparison between histopathologic findings and indocyanine green angiographic findings in Lewis rats with experimental autoimmune uveoretinitis
 Jpn J Ophthalmol (Masaoka N, Takahashi A, Fukushima A) 44/, 620-626 2000 (学術雑誌)

Effects of IL-4 and IL-12 on experimental immune-mediated blepharoconjunctivitis in Brown Norway rats
 Clin Exp Immunol (Ozaki A, Fukushima A, Fukata K, Ueno H (corresponding author)) 122/, 28-34 2000 (学術雑誌)

Comparison of genetic susceptibility to experimental allergic blepharo-conjunctivitis (EAC) between Lewis and Fischer rats
 Graefe’s Arch Clin Exp Ophthalmol (Yoshida O, Yoshida H, Iwamoto H, Nishino K, Fukushima A, Ueno H (corresponding author)) 236/, 859-864 1998 (学術雑誌)

Genetic background determines the nature of immune responses and experimental immune-mediated blepharoconjunctivitis (EC)
 Curr Eye Res (Yoshida O, Yoshida H, Iwamoto H, Nishino K, Fukushima A, Ueno H (corresponding author)) 18/, 117-124 1999 (学術雑誌)

Inhibitory effects of FK506 on the development of experimental allergic/immune-mediated blepharoconjunctivitis (EAC) in Lewis rats by systemic not but by topical administration
 Graefe’s Arch Clin Exp Ophthalmol (Iwamoto H, Yoshida H, Yoshida O, Fukushima A, Ueno H (corresponding author)) 237/, 407-414 1999 (学術雑誌)

Suppression of induction of experimental immune-mediated blepharoconjunctivitis (EC) by tolerogenic conjugates of the antigen and monomethoxypolyethylene glycol (mPEG)
 Br J Ophthalmol (Fukushima A, Nishino K, Yoshida H, Takata M, Ueno H (corresponding author)) 83/, 973-979 1999 (学術雑誌)

Fluorescein angiographic findings in a case of cancer-associated retinopathy
 Retina (Masaoka N, Emoto Y, Sasaoka A, Fukushima A, Ueno H, Ohguro H) 19/, 462-464 1999 (学術雑誌)

Uveitis induced by lymphocytes sensitized against a transgenically expressed lens protein
 Invest Ophthalmol Vis Sci (Lai JC, Lobanoff MC, Fukushima A, Wawrousek EF, Chan C.-C., Whitcup SM, Gery I (equally contributed as the first author)) 40/, 2735-2739 1999 (学術雑誌)

■ 研究業績(著書)

■ 研究業績(口頭・ポスター)

■ 研究業績(特許)

■ 研究業績(その他の活動)
イブジラストのアレルギー性結膜炎への効果(2000, 2001)受託研究等

通年性アレルギー性結膜炎モデルの作成とその発症におけるシクロスポリン点眼液の効果の検討(2004,2005)受託研究等

アレルギー性結膜炎における涙液中PAF濃度の測定(2005)受託研究等


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